Mutation - pgsA10

Mutation - pgsA10Mutation pgsA10

Mutation pgsA10

Name: pgsA10
Type: Base Pair Substitution
Mutation of Gene: pgsA
Approx. Map Location: 42.90
Comments
- Ref. below shows mutation substitutes a T for the C in an ACA (Thr) codon of pgsA10, substituting Ile in hydrophob.reg. Lowers in vitro PGP synthase act. but not acidic-phospholipid synthesis in vivo.
References
- Usui, M., H. Sembongi, H. Matsuzaki, K. Matsumoto, I. Shibuya 1994. Primary structures of the wild-type and mutant alleles encoding the phosphatidylglycerophosphate synthase of Escherichia coli. J.Bacteriol. 176:3389-3392
1 Strains Carrying This Mutation
Name Mutations Genotype
R477-100 14 F-, thr-1, araC14, leuB6(Am), fhuA1, lacY1, tsx-78, Δ(galK-attLAM)99, pgsA10, hisG4(Oc), rfbC1, rpsL136(strR), xylA5, mtl-1, thiE1