Product beta-hydroxydecanoylthioester dehydrase
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introduces cis double bond into growing acyl chain to give the unsaturated f.a. of E.coli. required for, but in WT does not limit rate of unsat. f.a. synth.
- Clark, D.P., D. DeMendoza, M. Polacco, J.E. Cronan 1983. Beta-hydroxydecanoyl thio ester dehydrase does not catalyze a rate-limiting step in Escherichia coli unsaturated fatty acid synthesis. Biochemistry 22:5897-0
- Sharma, A., B.S. Henderson, J.M. Schwab, J.L. Smith 1990. Crystallization and preliminary X-ray analysis of beta-hydroxydecanoyl thiol ester dehydrase from Escherichia coli. J.Biol.Chem. 265:5110-5112