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Product tryptophanase
| tryptophanase |
trp->indole,pyr,ammonia;also degrades cys,Mecys, &ser;can also catalyze condens.ofcys or ser with indole->trp,thus under approp.cond. synthesizes! trp.
- Newton, W.A., E.E. Snell 1962. Catalytic properties of tryptophanase, a multifunctional pyridoxal phosphate enzyme. Proc.Natl.Acad.Sci.USA 51:382-389
- Kazarinoff, M.N., E.E. Snell 1977. Essential arginine residues in tryptophanase from Escherichia coli. J.Biol.Chem. 252:7598-7602
- Phillips, R.S., N. Johnson, A.V. Kamath 2002. Formation in vitro of hybrid dimers of H463F and Y74F mutant Escherichia coli tryptophan indole-lyase rescues activity with L-tryptophan. Biochemistry 41:4012-4019