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Product 2-methylisocitrate lyase
| 2-methylisocitrate lyase |
32kDa subunit, homotetrameric enzyme. cleaves 2-methylisocitrate to succinate and pyruvate, last step propionate oxidation path. No activity with isocitrate.
- Brock, M., D. Darley, S. Textor, W. Buckel 2001. 2-Methylisocitrate lyases from the bacterium Escherichia coli and the filamentous fungus Aspergillus nidulans: characterization and comparison of both enzymes. Eur.J.Biochem. 268:3577-3586
- Grimm, C., A. Evers, M. Brock, C. Maerker, G. Klebe, W. Buckel, K. Reuter 2003. Crystal structure of 2-methylisocitrate lyase (PrpB) from Escherichia coli and modelling of its ligand bound active centre. J.Mol.Biol. 328:609-621