Site alaS
- Name: alaS
- Type: Gene
- Synonyms
act ala-act b2697 MG1655 locus tag lovB low volume; see Vinella et al. - Mnemonic: Alanine
- Left End Point: 60.73
- Right End Point: 60.79
- Products:
alanyl-tRNA synthetase (ligase) - Direction: <
- Priority: 1
- 6 Alleles of This Gene
alaS3(ts) alaS4(ts) alaS5(ts) alaS6(ts) alaS772(del)::kan alaS791-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank J01581 EcoGene.org EG10034 EcoliWiki alaS - Comment:
- Selectable Pheno. In thyA-; resistance to thymineless death. See also Bouloc et al. 1989 EMBO J 8:317 for lov mutant; Vinella et al.
- References:
- Kaplan, S., D. Anderson 1968. Selection of temperature-sensitive activating enzyme mutants in Escherichia coli. J.Bacteriol. 95:991-997
- Putney, S.D., D.L. Melendez, P. Schimmel 1981. Cloning, partial sequencing, and in vitro transcription of the gene for alanine tRNA synthetase. J.Biol.Chem. 256:205-211
- Putney, S.D., P. Schimmel 1981. An aminoacyl tRNA synthetase binds to a specific DNA sequence and regulates its gene transcription. Nature 291:632-635
- Putney, S.D., N.J. Royal, H. Neuman de Vegvar, W.C. Herlihy, K. Biemann, P. Schimmel 1981. Primary structure of a large aminoacyl-tRNA synthetase. Science 213:1497-1500
- Kondo, K., S. Wakabayashi, T. Yagi, H. Kagamiyama 1984. The complete amino acid sequence of aspartate aminotransferase from Escherichia coli: sequence comparison with pig isoenzymes. Biochem.Biophys.Res.Commun. 122:62-67
- Bouloc, P., A. Jaffe, R. D'Ari 1989. The Escherichia coli lov gene product connects peptidoglycan synthesis, ribosomes and growth rate [published erratum appears in EMBO J. 1989 (Apr.): 1290. EMBO J. 8:317-323
- Vinella, D., R. D'Ari, P. Bouloc 1992. Penicillin binding protein 2 is dispensable in Escherichia coli when ppGpp synthesis is induced. EMBO J. 11:1493-1501