Pay an invoice 
Site adhE
- Name: adhE
- Type: Gene
- Synonyms
adhC regulatory region for adhE (''adhC" at 27 min.) ana anaerobic alcohol/aldehyde deHase;probable regul.region of adhE b1241 MG1655 locus tag - Mnemonic: alcohol/acetald.dehydrogenase
- Left End Point: 27.91
- Right End Point: 27.97
- Products:
alcohol dehydrogenase, acetaldehyde dehydrogenase, CoA-linked - Direction: >
- Properties:
Property Comment encodes multifctnl.polypept. alcohol/aldehyde deHase and deactivase that regulates pyruvate formate lyase - Priority: 1
- 7 Alleles of This Gene
adhE1 adhE16(ts) adhE2 adhE36 adhE38 adhE748(del)::kan adhE80 - External Database Links:
Host Site Page Links EcoGene.org EG10031 EcoliWiki adhE - Comment:
- CoA-linked acetaldehyde dehydrogenase and alcohol dehydrogenase. Also regl.deactivase for pyr-formate lyase. Selectable Pheno. Loss: allyl alcohol resistance .
- References:
- Lorowitz, W., D.P. Clark 1982. Mutants of Escherichia coli with a temperature-sensitive alcohol dehydrogenase. J.Bacteriol. 152:935-938
- Cunningham, P.R., D.P. Clark 1986. The use of suicide substrates to select mutants of Escherichia coli lacking enzymes of alcohol fermentation. Mol.Gen.Genet. 205:487-493
- Goodlove, P.E., P.R. Cunningham, J. Parker, D.P. Clark 1989. Cloning and sequence analysis of the fermentative alcohol-dehydrogenase-encoding gene of Escherichia coli. Gene 85:209-214
- Leonardo, MR, DP Clark 1991. Locations of genes in the nar-adhE region of the Escherichia coli K-12 chromosome. J. Bacteriol. 173(5):1574-5.
- Chen, Y.-M., E.C.C. Lin 1991. Regulation of the adhE gene, which encodes ethanol dehydrogenase in Escherichia coli. J.Bacteriol. 173:8009-8013
- Kessler, D.P., I. Leibrecht, J. Knappe 1991. Pyruvate-formate-lyase-deactivase and acetyl-CoA reductase activities of Escherichia coli reside on a polymeric protein particle encoded by adhE. FEBS Lett. 281:59-63
- Gutheil, W.G., B. Holmquist, B.L. Vallee 1992. Purification, characterization and partial sequence of the glutathione-dependent formaldehyde dehydrogenase from Escherichia coli: a class III alcohol dehydrogenase. Biochemistry 31:475-481
- Leonardo, M.R., P.R. Cunningham, D.P. Clark 1993. Anaerobic regulation of the adhE gene, encoding the fermentative alcohol dehydrogenase of Escherichia coli. J.Bacteriol. 175:870-878
- Leonardo, M.R., Y. Dailly, D.P. Clark 1996. Role of NAD in regulating the adhE gene of Escherichia coli. J.Bacteriol. 178:6013-6018
- Aristarkhov, A., A. Mikulskis, J.G. Belasco, E.C. Lin 1996. Translation of the adhE transcript to produce ethanol dehydrogenase requires RNase III cleavage in Escherichia coli. J.Bacteriol. 178:4327-4332