Site mcrA
- Name: mcrA
- Type: Gene
- Synonyms
b1159 MG1655 locus tag rglA - Mnemonic: methylcytosine restriction
- Left End Point: 26.07
- Right End Point: 26.09
- Direction: >
- Properties:
Property Comment e14 within locus of e14. - Priority: 1
- 2 Alleles of This Gene
mcrA0 mcrA747(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10573 EcoliWiki mcrA - Comment:
- restriction of DNA at 5-methyl cytosine
- References:
- Ravi, R.S., S. Sozhamannan, K. Dharmalingam 1985. Transposon mutagenesis and genetic mapping of the rglA and rglB loci of Escherichia coli. Mol.Gen.Genet. 198:390-392
- Raleigh, E.A., G. Wilson 1986. Escherichia coli K-12 restricts DNA containing 5-methylcytosine. Proc.Natl.Acad.Sci.USA 83:9070-9074
- Raleigh, E.A., R. Trimarchi, H. Revel 1989. Genetic and physical mapping of the mcrA (rflA) and mcrB (rglB) loci of Escherichia coli K-12. Genetics 122:279-296
- Hiom, K., S.G. Sedgwick 1991. Cloning and structural characterization of the mcrA locus of Escherichia coli. J.Bacteriol. 173:7368-7373
- Raleigh, E.A., J. Benner, P. Bloom, H.D. Braymer, E. DeCruz, K. Dharmalingam, J. Heitman, M. Noyer Weidner, A. Piekarowicz, P. Kretz, et al 1991. Nomenclature relating to restriction of modified DNA in Escherichia coli. J.Bacteriol. 173:2707-2709
- Anton, B.P., E.A. Raleigh 2004. Transposon-mediated linker insertion scanning mutagenesis of the Escherichia coli McrA endonuclease. J.Bacteriol. 186:5699-5707