Site sodB
- Name: sodB
- Type: Gene
- Synonyms
b1656 MG1655 locus tag - Mnemonic: SOD, superoxide dismutase
- Left End Point: 37.36
- Right End Point: 37.38
- Products:
superoxide dismutase, Fe - Direction: >
- Properties:
Property Comment iron uptake regulon probable member, but no Fe-dependent repression - Priority: 1
- 1 Alleles of This Gene
sodB734(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank J03511 EcoGene.org EG10954 EcoliWiki sodB - Comment:
- Protects against metal stress. Shown to be regulated by Fur.
- References:
- Grogan, D.W., J.E. Cronan 1984. Genetic characterization of Escherichia coli cyclopropane fatty acid (cfa) locus and neighboring loci. Mol.Gen.Genet. 196:367-372
- Nettleton, C.J., C. Bull, T.O. Baldwin, J.A. Fee 1984. Isolation of the Escherichia coli iron superoxide dismutase gene: evidence that intracellular superoxide concentration does not regulate oxygen-dependent synthesis of the manganese superoxide dism
- Carlioz, A., D. Touati 1986. Isolation of superoxide dismutase mutants in Escherichia coli: is superoxide dismutase necessary for aerobic life?. EMBO J. 5:623-630
- Schinina, M.E., L. Maffey, D. Barra, F. Bossa, K. Puget, A.M. Michelson 1987. The primary structure of iron superoxide dismutase from Escherichia coli. FEBS Lett. 221:87-90
- Carlioz, A., M.L. Ludwig, W.C. Stallings, J.A. Fee, H.M. Steinman, D. Touati 1988. Iron superoxide dismutase: nucleotide sequence of the gene from Escherichia coli K12 and correlations with crystal structures. J.Biol.Chem. 263:1555-1562
- Niederhoffer, E.C., C.M. Naranjo, K.L. Bradley, J.A. Fee 1990. Control of Escherichia coli superoxide dismutase (sodA and sodB) genes by the ferric uptake regulation (fur) locus. J.Bacteriol. 172:1930-1938
- Fee, J.A. 1991. Regulation of sod genes in Escherichia coli: relevance to superoxide dismutase function. Mol.Microbiol. 5:2599-2610
- Keyer, K., A.S. Gort, J.A. Imlay 1995. Superoxide and the production of oxidative DNA damage. J.Bacteriol. 177:6782-6790
- Benov, L., I. Fridovich 1995. A superoxide dismutase mimic protects sodA sodB Escherichia coli against aerobic heating and stationary-phase death. Arch.Biochem.Biophys. 322:291-294
- Benov, L., I. Fridovich 1998. Growth in iron-enriched medium partially compensates Escherichia coli for the lack of manganese and iron superoxide dismutase. J.Biol.Chem. 273:10313-10316
- Geslin, C., J. Llanos, D. Prieur, C. Jeanthon 2001. The manganese and iron superoxide dismutases protect Escherichia coli from heavy metal toxicity. Res.Microbiol. 152:901-905
- Masse, E., S. Gottesman 2002. A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli. Proc.Natl.Acad.Sci.USA 99:4620-4625
- Bebien, M., G. Lagniel, J. Garin, D. Touati, A. Vermeglio, J. Labarre 2002. Involvement of superoxide dismutases in the response of Escherichia coli to selenium oxides. J.Bacteriol. 184:1556-1564