E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

About the CGSC

• CGSC Home
• Scope of the Collection
• The Database
• Privacy Policy
• Acknowledgment of Support

Searching the CGSC Database

• Help With Query Forms
• Strain Query
• Mutation Query
• Gene/Site Query
• Gene Product Query
• Reference Query
• Query Help
• Info on Genetic Nomenclature

How to Request Strains or Information

• Contact Information
• Charges
• Reviving Strains
• Strains Not Found?

Other CGSC Information

• FAQ on Procedures
• Current Working Map
• 1998 MMBR Map
• 1998 MMBR Gene List
• Map Diagrams (PDFs)

Other Links

• E. coli Links
• Other Stock Collections
• Other Bio Links
• Yale Web

Funded by a grant from the National Science Foundation

Site rdgB

• Name: rdgB
• Type: Gene
  Synonyms

  b2954	MG1655 locus tag
  yggV

  
  
• Mnemonic: RecA dependent growth
• Left End Point: 66.71
• Right End Point: 66.72
  Products:

  inosine/xanthosine triphosphatase

  
  
• Direction: >
• Properties:

  Property	Comment
  repair system gene	suppresses fragmentation after double-strand break; prevents incorporation of dITP/dXTP

  
  
• Priority: 1
  2 Alleles of This Gene

  rdgB728(del)::kan

  rdgB791-YFP(::cat)

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG12982
  EcoliWiki	rdgB

  
  
• Comment:
  • Mutant growth/viability dependent on recA. rdgB/recA double mutant is lethal, but suppressed by inactivation of Endonuclease V (nfi). rdgB/recBC cells are also inviable, rdgB/recF cells are OK
• References:
  • Clyman, J., R.P. Cunningham 1987. Escherichia coli K-12 mutants in which viability is dependent on recA function. J.Bacteriol. 169:4203-4210
  
  
  • Bradshaw, J.S., A. Kuzminov 2003. RdgB acts to avoid chromosome fragmentation in Escherichia coli. Mol.Microbiol. 48:1711-1725