Site fur
- Name: fur
- Type: Gene
- Synonyms
b0683 MG1655 locus tag - Mnemonic: ferric uptake regulation
- Left End Point: 15.29
- Right End Point: 15.30
- Products:
global regulator of ferric ion uptake - Direction: <
- Priority: 1
- 3 Alleles of This Gene
fur-1::Tn5 fur-731(del)::kan fur-791-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank X02589 EcoGene.org EG10359 EcoliWiki fur - Comment:
- Ferric iron uptake; negative regulatory gene,
- References:
- Hantke, K. 1984. Cloning of the repressor protein gene of iron-regulated systems in Escherichia coli K12. Mol.Gen.Genet. 197:337-341
- Bagg, A., J.B. Neilands 1985. Mapping of a mutation affecting regulation of iron uptake systems in Escherichia coli K-12. J.Bacteriol. 161:450-453
- Schaffer, S., K. Hantke, V. Braun 1985. Nucleotide sequence of the iron regulatory gene fur. Mol.Gen.Genet. 200:110-113
- Bagg, A., J.B. Neilands 1987. Ferric uptake regulation protein acts as a repressor, employing iron (II) as a cofactor to bind the operator of an iron transport operon in Escherichia coli. Biochemistry 26:5471-5477
- De Lorenzo, V., M. Herrero, F. Giovannini, J.B. Neilands 1988. Fur (ferric uptake regulation) protein and CAP (catabolite-activator protein) modulate transcription of fur gene in Escherichia coli. Eur.J.Biochem. 173:537-546
- Niederhoffer, E.C., C.M. Naranjo, K.L. Bradley, J.A. Fee 1990. Control of Escherichia coli superoxide dismutase (sodA and sodB) genes by the ferric uptake regulation (fur) locus. J.Bacteriol. 172:1930-1938
- Neilands, J.B. 1995. Siderophores: structure and function of microbial iron transport compounds. J.Biol.Chem. 270:26723-26726
- Hoerter, J., A. Pierce, C. Troupe, J. Epperson, A. Eisenstark 1996. Role of enterobactin and intracellular iron in cell lethality during near-UV irradiation in Escherichia coli. Photochem.Photobiol. 64:537-541
- Zheng, M., B. Doan, T.D. Schneider, G. Storz 1999. OxyR and SoxRS regulation of fur. J.Bacteriol. 181:4639-4643
- Vassinova, N., D. Kozyrev 2000. A method for direct cloning of fur-regulated genes: identification of seven new fur-regulated loci in Escherichia coli. Microbiology 146:3171-3182