Site cspA
- Name: cspA
- Type: Gene
- Synonyms
b3556 MG1655 locus tag - Mnemonic: cold shock protein
- Left End Point: 80.14
- Right End Point: 80.14
- Products:
cold shock protein CS7.4 - Direction: >
- Properties:
Property Comment cold shock response regulon NULL transcription factor gene NULL regulatory gene NULL encodes NA-binding protein NULL - Priority: 0
- 2 Alleles of This Gene
cspA740(del)::kan cspA791-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank M30139 EcoGene.org EG10166 EcoliWiki cspA - Comment:
- High similarity with Y-box DNA-binding proteins of eukaryotes
- References:
- Goldstein, J., N.S. Pollitt, M. Inouye 1990. Major heat shock protein of Escherichia coli. Proc.Natl.Acad.Sci.USA 87:283-287
- Tanabe, H., J. Goldstein, M. Yang, M. Inouye 1992. Identification of the promoter region of the Escherichia coli major cold shock gene, cspA. J.Bacteriol. 174:3867-3873
- Jones, P.G., R. Krah, S.R. Tafuri, A.P. Wolffe 1992. DNA gyrase, CS7.4, and the cold shock response in Escherichia coli. J.Bacteriol. 174:5798-5802
- Lee, S.J., A. Xie, W. Jiang, J.P. Etchegaray, P.G. Jones, M. Inouye 1994. Family of the major cold-shock protein CspA (CS7.4) of Escherichia coli, whose members show a high sequence similarity with the eukaryotic Y-box binding proteins. Mol.Microbiol.
- Brandi, A., P. Pietroni, C.O. Gualerzi, C.L. Pon 1996. Post-transcriptional regulation of CspA expression in Escherichia coli. Mol.Microbiol. 19:231-240
- Fang, L., W. Jiang, W. Bae, M. Inouye 1997. Promoter-independent cold-shock induction of cspA and its derepression at 37 degrees C by mRNA stabilization. Mol.Microbiol. 23:355-364
- Goldenberg, D., I. Azar, A.B. Oppenheim, A. Brandi, C.L. Pon, C.O. Gualerzi 1997. Role of Escherichia coli cspA promoter sequences and adaptation of translational apparatus in the cold shock response. Mol.Gen.Genet. 256:282-290
- Bae, W., P.G. Jones, M. Inouye 1997. CspA, the major cold shock protein of Escherichia coli, negatively regulates its own gene expression. J.Bacteriol. 179:7081-7088
- Jiang, W., Y. Hou, M. Inouye 1997. CspA, the major cold-shock protein of Escherichia coli, is an RNA chaperone. J.Biol.Chem. 272:196-202
- Yamanaka, K., L. Fang, M. Inouye 1998. The CspA family in Escherichia coli: multiple gene duplication for stress adaptation. Mol.Microbiol. 27:247-255
- Fang, L., Y. Hou, M. Inouye 1998. Role of the cold-box region in the 5' untranslated region of the cspA mRNA in its transient expression at low temperature in Escherichia coli. J.Bacteriol. 180:90-95
- Brandi, A., R. Spurio, C.O. Gualerzi, C.L. Pon 1999. Massive presence of the Escherichia coli 'major cold-shock protein' CspA under non-stress conditions. EMBO J. 18:1653-1659
- Xia, B., H. Ke, W. Jiang, M. Inouye 2002. The Cold Box stem-loop proximal to the 5'-end of the Escherichia coli cspA gene stabilizes its mRNA at low temperature. J.Biol.Chem. 277:6005-6011