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Site bolA
- Name: bolA
- Type: Gene
- Synonyms
b0435 MG1655 locus tag - Mnemonic: bolus
- Left End Point: 9.78
- Right End Point: 9.79
- Direction: >
- Properties:
Property Comment affects cell division/growth NULL - Priority: 0
- 3 Alleles of This Gene
bolA2::kan bolA721(del)::kan bolA791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10125 EcoliWiki bolA - Comment:
- morphogene. produces osmotically stable spherical cells when overexpressed (dependent on presence of FtsZ). Suggests mechanism mediated by FtsZ that modifies conform. of nascent murein in septum form.
- References:
- Aldea, M., C. Hernandez-Chico, A.G. de la Campa, S.R. Kushner, M. Vicente 1988. Identification, cloning, and expression of bolA, an ftsZ-dependent morphogene of Escherichia coli. J.Bacteriol. 170:5169-5176
- Aldea, M., T. Garrido, C. Hernandez-Chico, M. Vicente, S.R. Kushner 1989. Induction of a growth-phase-dependent promoter triggers transcription of bolA, an Escherichia coli morphogene. EMBO J. 8:3923-3931
- Aldea, M., T. Garrido, J. Pla, M. Vicente 1990. Division genes in Escherichia coli are expressed coordinately to cell septum requirements by gearbox promoters. EMBO J. 9:3787-3794
- Lange, R., R. Hengge-Aronis 1991. Growth phase-regulated expression of bolA and morphology of stationary-phase Escherichia coli cells are controlled by the novel sigma factor sigma S. J.Bacteriol. 173:4474-4481