Site clpP
- Name: clpP
- Type: Gene
- Synonyms
b0437 MG1655 locus tag F21.5 gene LopP - Mnemonic: caseinolytic protease
- Left End Point: 9.83
- Right End Point: 9.84
- Products:
ClpP ATP-dependent protease Ti proteolytic subunit - Direction: >
- Properties:
Property Comment encodes a protease NULL heat shock regulon NULL - Priority: 0
- 3 Alleles of This Gene
clpP101(del-ins)::cat clpP723(del)::kan clpP793-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10158 EcoliWiki clpP - Comment:
- References:
- Maurizi, M.R., W.P. Clark, Y. Katayama, S. Rudikoff, J. Pumphrey, B. Bowers, S. Gottesman 1990. Sequence and structure of ClpP, the proteolytic component of the ATP-dependent Clp protease of Escherichia coli. J.Biol.Chem. 265:12536-12545
- Kroh, H.E., L.D. Simon 1990. The ClpP component of Clp protease is the sigma 32-dependent heat shock protein F21.5. J.Bacteriol. 172:6026-6034
- Maurizi, M.R. 1991. ATP-promoted interaction between ClpA and ClpP in activation of Clp protease from Escherichia coli. Biochem.Soc.Trans. 19:719-723
- Wojkowiak, D., C. Georgopoulos, M. Zylicz 1993. Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli. J.Biol.Chem. 268:22609-22617
- Seol, J.H., K.M. Woo, M.S. Kang, D.B. Ha, C.H. Chung 1995. Requirement of ATP hydrolysis for assembly of ClpA/ClpP complex, the ATP-dependent protease Ti in Escherichia coli. Biochem.Biophys.Res.Commun. 217:41-51
- Bohn, C., E. Binet, P. Bouloc 2002. Screening for stabilization of proteins with a trans-translation signature in Escherichia coli selects for inactivation of the ClpXP protease. Molecular Genetics & Genomics: MGG 266:827-831