Site pyrI
- Name: pyrI
- Type: Gene
- Synonyms
b4244 MG1655 locus tag - Mnemonic: Pyrimidine
- Left End Point: 96.32
- Right End Point: 96.33
- Products:
aspartate carbamoyltransferase, regulatory subunit aspartate transcarbamylase, regulatory subunit - Direction: <
- Properties:
Property Comment auxotrophy-pur/pyr NULL - Priority: 1
- 1 Alleles of This Gene
pyrI720(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank K01472 NCBI/GenBank J01670 EcoGene.org EG10811 EcoliWiki pyrI - Comment:
- References:
- Pierard, A., N. Glansdorff, D. Gigot, M. Crabeel, P. Halleux, L. Thiry 1976. Repression of Escherichia coli carbamoylphosphate synthase: relationships with enzyme synthesis in the arginine and pyrimidine pathways. J.Bacteriol. 127:291-301
- Wild, J.R., F. Foltermann, W.D. Roof, G.A. O'Donovan 1981. A mutation in the catalytic cistron of aspartate carbamoyltransferase affecting catalysis, regulatory response and holoenzyme assembly. Nature 292:373-375
- Feller, A., A. Pierard, N. Glansdorff, D. Charlier, M. Crabeel 1981. Mutation of gene encoding regulatory polypeptide of aspartate carbamoyltransferase. Nature 292:370-373
- Roof, W.D., F. Foltermann, J.R. Wild 1982. The organization and regulation of the pyrBI operon in E. coli includes a Rho-independent attenuator sequence. Mol.Gen.Genet. 187:391-400
- Pauza, C.D., M.J. Karels, M. Navre, H.K. Schachman 1982. Genes encoding Escherichia coli aspartate transcarbomoylase: the pyrB-pyrI operon. Proc.Natl.Acad.Sci.USA 79:4020-4024
- Hoover, T.A., W.D. Roof, K.F. Folterman, G.A. O'Donovan, D.A. Bencini, J.R. Wild 1983. Nucleotide sequence of the structural gene (pyrB) that encodes the catalytic polypeptide of aspartate transcarbamoylase of Escherichia coli. Proc.Natl.Acad.Sci.USA 8
- Roland, K.L., F.E. Powell, C.L. Turnbough 1985. Role of translation and attenuation in the control of pyrBI operon expression in Escherichia coli K-12. J.Bacteriol. 163:991-999
- Levin, H.L., H.K. Schachman 1985. Regulation of aspartate transcarbamoylase synthesis in Escherichia coli: analysis of deletion mutations in the promoter region of the pyrBI operon. Proc.Natl.Acad.Sci.USA 82:4643-4647