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Site barA
- Name: barA
- Type: Gene
- Synonyms
b2786 MG1655 locus tag - Mnemonic: bacterial adaptive response
- Left End Point: 62.79
- Right End Point: 62.85
- Products:
sensor kinase protein BarA - Direction: >
- Properties:
Property Comment encodes membrane protein NULL encodes memb.of multimer.compl EnvZ, OmpR family of regulatory factors encodes signal transducer see Ishige et al. encodes memb.of multimer.compl tripartite sensors of 2-component signal transduction system - Priority: 0
- 4 Alleles of This Gene
barA1358(del) barA614(del) barA784(del)::kan barA791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG11367 EcoliWiki barA - Comment:
- Cognate=UvrY. like OmpR \& EnvZ has 'sensory kinase domain' /& 'response regulator domain'.in isolated membranes undergoes P'n in pres.of ATP.In high copy,BarA suppresses envZ-mutant defects in ompCF;
- References:
- Nagasawa, S., S.. Tokishita, H. Aiba, T. Mizuno 1992. A novel sensor-regulator protein that belongs to the homologous family of signal-transduction proteins involved in adaptive responses in Escherichia coli. Mol.Microbiol. 6:799-807
- Ishige, K., S. Nagasawa, S.. Tokishita, T. Mizuno 1994. A novel device of bacterial signal transducers. EMBO J. 13:5195-5202
- Pernestig, A.K., O. Melefors, D. Georgellis 2001. Identification of UvrY as the cognate response regulator for the BarA sensor kinase in Escherichia coli. J.Biol.Chem. 276:225-231