Site deaD
- Name: deaD
- Type: Gene
- Synonyms
b3162 MG1655 locus tag csdA Jones et al. as proposed new name mssB for multicopy suppressor - Mnemonic: DEAD motif
- Left End Point: 71.21
- Right End Point: 71.25
- Products:
ribosome-associated protein that unwinds ds RNA DEAD-box helicase - Direction: <
- Properties:
Property Comment encodes helicase D-E-A-D family of proteins - Priority: 0
- 2 Alleles of This Gene
deaD774(del)::kan deaD791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10215 EcoliWiki deaD - Comment:
- gene-dosage-dependent suppressor of temperature-sensitive mutations in rpsB, encoding ribosomal protein S2. Can unwind ds RNA in absence of ATP
- References:
- Toone, M., K.E. Rudd, J.D. Friesen 1991. deaD, a new Escherichia coli gene encoding a presumed ATP-dependent RNA helicase, can suppress a mutation in rpsB, the gene encoding ribosomal protein S2. J.Bacteriol. 173:3291-3302
- Yamanaka, K., T. Ogura, E.V. Koonin, H. Niki, S. Hiraga 1994. Multicopy suppressors, mssA and mssB, of an smbA mutation of Escherichia coli. Mol.Gen.Genet. 243:9-16
- Jones, P.G., M. Mitta, Y. Kim, W. Jiang, M. Inouye 1996. Cold shock induces a major ribosomal-associated protein that unwinds double-stranded RNA in Escherichia coli. Proc.Natl.Acad.Sci.USA 93:76-80
- Fang, L., Y. Hou, M. Inouye 1998. Role of the cold-box region in the 5' untranslated region of the cspA mRNA in its transient expression at low temperature in Escherichia coli. J.Bacteriol. 180:90-95