Site rph
- Name: rph
- Type: Gene
- Synonyms
b3643 MG1655 locus tag - Mnemonic: RNase PH
- Left End Point: 82.20
- Right End Point: 82.22
- Products:
RNase PH phosphorolytic ribonuclease ribonuclease PH - Direction: <
- Priority: 0
- 2 Alleles of This Gene
rph-1 rph-749(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10863 EcoliWiki rph - Comment:
- References:
- Poulsen, P., J.T. Andersen, K.F. Jensen 1989. Molecular and mutational analysis of three genes preceding pyrE on the Escherichia coli chromosome. Mol.Microbiol. 3:393-404
- Ost, K.A., M.P. Deutscher 1991. Escherichia coli orfE (upstream of pyrE) encodes RNase PH. J.Bacteriol. 173:5589-5591
- Andersen, J.T., P. Poulsen, K.F. Jensen 1992. Attenuation in the rph-pyrE operon of Escherichia coli and processing of the dicistronic mRNA. Eur.J.Biochem. 206:381-390
- Kelly, K.O., N.B. Reuven, Z.-W. Li, M.P. Deutscher 1992. RNase PH is essential for tRNA processing and viability in RNase-deficient Escherichia coli cells. J.Biol.Chem. 267:16015-16018
- Jensen, K.F., J.T. Andersen, P. Poulsen 1992. Overexpression and rapid purification of the orfE/rph gene product, RNase PH of Escherichia coli. J.Biol.Chem. 267:17147-17152
- Jensen, K.F. 1993. The Escherichia coli K-12 "wild types" W3110 and MG1655 have an rph frameshift mutation that leads to pyrimidine starvation due to low pyrE expression levels. J.Bacteriol. 175:3401-3407