Site dipZ
- Name: dipZ
- Type: Gene
- Synonyms
b4136 MG1655 locus tag ccm? cytochrome c maturation? cutA2 cycZ dsbD - Mnemonic: disulfide isomerase protein
- Left End Point: 94.00
- Right End Point: 94.04
- Products:
DsbD membrane protein in pathway for reduction of cysteines of DSB isomerases - Direction: <
- Priority: 0
- 2 Alleles of This Gene
dipZ4::Cm dipZ762(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG12178 EcoliWiki dipZ - Comment:
- can't use cyc for cycloserine-R and now for cytochrome c-like. affects disulfide-binding but not a disulfide-binding protein. proposed new nomenclature
- References:
- Stewart, P.S., R. D'Ari 1992. Genetic and morphological characterization of an Escherichia coli chromosome segregation mutant. J.Bacteriol. 174:4513-4516
- Crooke, H., J.A. Cole 1994. The biogenesis of c-type cytochromes in Escherichia coli requires an integral membrane protein with a protein disulphide isomerase like domain. GenBank submission X77:707
- Beck, R., H. Crooke, M. Jarsch, J.A. Cole, H. Burtscher 1994. Mutation in dipZ leads to reduced production of active human placental alkaline phosphatase in Escherichia coli. FEMS Microbiol.Lett. 124:209-214
- Sambongi, Y., H. Crooke, J.A. Cole, S.J. Ferguson 1994. A mutation blocking the formation of membrane or periplasmic endogenous and exogenous c-type cytochromes in Escherichia coli permits the cytoplasmic formation of Hydrogenobacter thermophilus holo
- Iobbi-Nivol, C., H. Crooke, L. Griffiths, J. Grove, H. Hussain, J. Pommier, V. Mejean, J.A. Cole 1994. A reassessment of the range of c-type cytochromes synthesized by Escherichia coli K-12. FEMS Microbiol.Lett. 119:89-94
- Missiakas, D., F. Schwager, S. Raina 1995. Identification and characterization of a new disulfide isomerase-like protein (DsbD) in Escherichia coli. EMBO J. 14:3415-3424
- Crooke, H., J. Cole 1995. The biogenesis of c-type cytochromes in Escherichia coli requires a membrane-bound protein, DipZ, with a protein disulphide isomerase-like domain. Mol.Microbiol. 15:1139-1150
- Metheringham, R., L. Griffiths, H. Crooke, S. Forsythe, J.A. Cole 1995. An essential role for DsbA in cytochrome c synthesis and formate-dependent nitrite reduction by Escherichia coli K-12. Arch.Microbiol. 164:301-307
- Stewart, E.J., F. Katzen, J. Beckwith 1999. Six conserved cysteines of the membrane protein DsbD are required for the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli. EMBO J. 18:5963-5971