Site csrA
- Name: csrA
- Type: Gene
- Synonyms
b2696 MG1655 locus tag zfiA Murayama et al. - Mnemonic: carbon storage regulator
- Left End Point: 60.72
- Right End Point: 60.73
- Products:
carbon storage regulator protein - Direction: <
- Properties:
Property Comment regulatory gene inhibits glycogen biosynthesis global regulation - Priority: 0
- 1 Alleles of This Gene
csrA791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG11447 EcoliWiki csrA - Comment:
- also involved with host response to let(ccd) genes of the F factor. Mutants have carbon stress in presence of acetate.
- References:
- Romeo, T., M. Gong, M.Y. Liu, A.M. Brun-Zinkernagel 1993. Identification and molecular characterization of csrA, a pleiotropic gene from Escherichia coli that affects glycogen biosynthesis, gluconeogenesis, cell size, and surface properties. J.Bacterio
- Romeo, T., M. Gong 1993. Genetic and physical mapping of the regulatory gene csrA on the Escherichia coli K-12 chromosome. J.Bacteriol. 175:5740-5741
- Sabnis, N.A., H. Yang, T. Romeo 1995. Pleiotropic regulation of central carbohydrate metabolism in Escherichia coli via the gene csrA. J.Biol.Chem. 270:29096-0
- Liu, M.Y., H. Yang, T. Romeo 1995. The product of the pleiotropic Escherichia coli gene csrA modulates glycogen biosynthesis via effects on mRNA stability. J.Bacteriol. 177:2663-2672
- Yang, H., M.Y. Liu, T. Romeo 1996. Coordinate genetic regulation of glycogen catabolism and biosynthesis in Escherichia coli via the CsrA gene product. J.Bacteriol. 178:1012-1017
- Murayama, N., H. Shimizu, S. Takiguchi, Y. Baba, H. Amino, T. Horiuchi, K. Sekimizu, T. Miki 1996. Evidence for involvement of Escherichia coli genes pmbA, csrA and a previously unrecognized gene tldD, in the control of DNA gyrase by letD (ccdB) of sex
- Wei, B., S. Shin, D. LaPorte, A.J. Wolfe, T. Romeo 2000. Global regulatory mutations in csrA and rpoS cause severe central carbon stress in Escherichia coli in the presence of acetate. J.Bacteriol. 182:1632-1640
- Tatarko, M., T. Romeo 2001. Disruption of a global regulatory gene to enhance central carbon flux into phenylalanine biosynthesis in Escherichia coli. Curr.Microbiol. 43:26-32