E. coli Genetic Resources at Yale
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Site rsuA

• Name: rsuA
• Type: Gene
  Synonyms

  b2183	MG1655 locus tag

  
  
• Mnemonic: RNA, small, pseudouridine
• Left End Point: 49.12
• Right End Point: 49.14
  Products:

  16S RNA pseudouridine 516 synthase, rRNA pseudouridylate 516 synthase.

  
  
• Direction: <
• Priority: 0
  2 Alleles of This Gene

  rsuA740(del)::kan

  rsuA791-YFP(::cat)

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG12044
  EcoliWiki	rsuA

  
  
• Comment:
  • Gene product catalyzes foramtion of pseudouridine (psi) at position 516 in 16S rRNA during assembly of the 30S ribosome.
• References:
  • Wrzesinski, J., A. Bakin, K. Nurse, B.G. Lane, J. Ofengand 1995. Purification, cloning, and properties of the 16S RNA pseudouridine 516 synthase from Escherichia coli. Biochemistry 34:8904-8913
  
  
  • Sivaraman, J., V. Sauve, R. Larocque, E.A. Stura, J.D. Schrag, M. Cygler, A. Matte 2002. Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol. 9:353-358