Site poxB
- Name: poxB
- Type: Gene
- Synonyms
b0871 MG1655 locus tag - Mnemonic: pyruvate oxidase
- Left End Point: 19.58
- Right End Point: 19.62
- Products:
pyruvate oxidase, stationary phase (rpoS-dependent) induction - Direction: >
- Properties:
Property Comment stationary phase(rpoS) regulon NULL - Priority: 1
- 4 Alleles of This Gene
poxB11 poxB14::kan poxB15::lacZ::CmR poxB772(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank X04105 EcoGene.org EG10754 EcoliWiki poxB - Comment:
- (Major C3 to C2 conversion is pyr to acetyl CoA via pyruvate dehydrogenase (aceEF).)
- References:
- Chang, Y.-Y., J.E. Cronan 1983. Genetic and biochemical analyses of Escherichia coli strains having a mutation in the structural gene (poxB) for pyruvate oxidase. J.Bacteriol. 154:756-762
- Grabau, C., J.E. Cronan 1984. Molecular cloning of the gene (poxB) encoding the pyruvate oxidase of Escherichia coli, a lipid-activated enzyme. J.Bacteriol. 160:1088-1092
- Grabau, C., J.E. Cronan 1986. Nucleotide sequence and deduced amino acid sequence of Escherichia coli pyruvate oxidase, a lipid-activated flavoprotein. Nucleic Acids Res. 14:5449-5460
- Chang, Y.Y., J.E. Cronan, S.J. Li, K. Reed, T. Vanden Boom, A.Y. Wang 1991. Locations of the lip, poxB, and ilvBN genes on the physical map of Escherichia coli. J.Bacteriol. 173:5258-4259
- Chang, Y.-Y., A.Y. Wang, J.E. Cronan 1994. Expression of Escherichia coli pyruvate oxidase (PoxB) depends on the sigma factor encoded by the rpoS(katF) gene. Mol.Microbiol. 11:1019-1028