Site pldA
- Name: pldA
- Type: Gene
- Synonyms
b3821 MG1655 locus tag - Mnemonic: phospholipase, detergent-resistant
- Left End Point: 86.28
- Right End Point: 86.29
- Products:
phospholipase A, detergent resistant OMPLA, outer membrane phospholipase A - Direction: <
- Priority: 1
- 4 Alleles of This Gene
pldA1 pldA20(del-ins)::kan pldA766(del)::kan pldA791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10738 EcoliWiki pldA - Comment:
- Selectable phenotype. Loss: resistance to EDTA-induced actinomycin D sensitivity.
- References:
- Voll, M.J., L. Leive 1970. Release of lipopolysaccharide in Escherichia coli resistant to the permeability increase induced by ethylenediaminetetraacetate. J.Biol.Chem. 245:1108-1114
- Hardaway, K.L., C.S. Buller 1979. Effects of ethylenediaminetetraacetate on phospholipids and outer membrane function in Escherichia coli. J.Bacteriol. 137:62-68
- Homma, H., T. Kobayashi, Y. Ito, I. Kudo, K. Inoue, H. Ikeda, M. Sekiguchi, S. Nojima 1983. Identification and cloning of the gene coding for lysophospholipase L2 of E. coli K-12. J.Biochem.(Tokyo) 94:2079-2081
- de Geus, P., I. van Die, H. Bergmans, J. Tommassen, G. de Haas 1983. Molecular cloning of pldA, the structural gene for outer membrane phospholipase of E. coli K12. Mol.Gen.Genet. 190:150-155
- Homma, H., T. Kobayashi, N. Chiba, K. Karasawa, H. Mizushima, I. Kudo, K. Inoue, H. Ikeda, M. Sekiguchi, S. Nojima 1984. The DNA sequence encoding pldA gene, the structural gene for detergent-resistant phospholipase A of E. coli. J.Biochem.(Tokyo) 96:1
- de Geus, P., H.M. Verheij, N.H. Riegman, W.P.M. Hoekstra, G. de Haas 1984. The pro- and mature forms of the E. coli K-12 outer membrane phospholipase A are identical. EMBO J. 3:1799-1802
- Kobayashi, T., I. Kudo, H. Homma, K. Karasawa, K. Inoue, H. Ikeda, S. Nojima 1985. Gene organization of pldA and pldB, the structural genes for detergent-resistant phospholipase A and lysophospholipase L2 of Escherichia coli. J.Biochem.(Tokyo) 98:1007-
- Aldea, M., V.F. Maples, S.R. Kushner 1988. Generation of a detailed physical and genetic map of the ilv-metE-udp region of the Escherichia coli chromosome. J.Mol.Biol. 200:427-438
- Daniels, D.L., G. Plunkett, V.D. Burland, F.R. Blattner 1992. Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes. Science 257:771-778
- Brok, R.G.P.M., E. Brinkman, R. van Boxtel, A.C.A.P.A. Bekkers, H.M. Verheij, J. Tommassen 1994. Molecular characterization of enterobacterial pldA genes encoding outer membrane phospholipase A. J.Bacteriol. 176:861-870