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Site sbmC
- Name: sbmC
- Type: Gene
- Synonyms
b2009 MG1655 locus tag gyrI - Mnemonic: sensitivity B16 microcin
- Left End Point: 44.81
- Right End Point: 44.82
- Products:
probably MccB17 sequestering protein DNA gyrase-inhibiting protein - Direction: <
- Properties:
Property Comment SOS-related NULL - Priority: 0
- 1 Alleles of This Gene
sbmC778(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11892 EcoliWiki sbmC - Comment:
- SbmC in high copy number protects cells from replication inhibitor microcin B17 MccB17. Induced by DNA-damaging agents (SOS) and in stat.phase. Blocks MccB17 export fromproducing cells.Gyr-inhibitor
- References:
- Baquero, M.R., M. Bouzon, J. Varea, F. Moreno 1995. sbmC, a stationary-phase induced SOS Escherichia coli gene, whose product protects cells from the DNA replication inhibitor microcin B17. Mol.Microbiol. 18:301-311
- Nakanishi, A., T. Oshida, T. Matsushita, S. Imajoh-Ohmi, T. Ohnuki 1998. Identification of DNA gyrase inhibitor (GyrI) in Escherichia coli. J.Biol.Chem. 273:1933-1938
- Nakanishi, A., S. Imajoh-Ohmi, F. Hanaoka 2002. Characterization of the interaction between DNA gyrase inhibitor and DNA gyrase of Escherichia coli. J.Biol.Chem. 277:8949-8954