E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site thiI

• Name: thiI
• Type: Gene
  Synonyms

  b0423	MG1655 locus tag
  nuvC?

  
  
• Mnemonic: thiamin (and thiazole)
• Left End Point: 9.50
• Right End Point: 9.53
• Direction: >
• Priority: 0
  1 Alleles of This Gene

  thiI780(del)::kan

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG13273
  EcoliWiki	thiI

  
  
• Comment:
  • converts uridine at position 8 of some tRNAs to 4-thiouridine, which serves as a photosensor for near-UV; also plays a role in thiamin biosynthesis
• References:
  • Mueller, E.G., C.J. Buck, P.M. Palenchar, L.E. Barnhart, J.L. Paulson 1998. Identification of a gene involved in the generation of 4-thiouridine in tRNA. Nucleic Acids Res. 26:2606-2610
  
  
  • Taylor, S.V., N.L. Kelleher, C. Kinsland, H.J. Chiu, C.A. Costello, A.D. Backstrom, F.W. McLafferty, T.P. Begley 1998. Thiamin biosynthesis in Escherichia coli.Identification of this thiocarboxylate as the immediate sulfur donor in the thiazole formati