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Site ispD
- Name: ispD
- Type: Gene
- Synonyms
b2747 Blattner et al. sequence label b2747 MG1655 locus tag ygbP temporary name ygbP Rudd map, EcoGene - Mnemonic: isoprenoid synthesis
- Left End Point: 61.86
- Right End Point: 61.87
- Products:
4-diphosphocytidyl-2-C-methylerythritol synthase - Direction: <
- Priority: 0
- External Database Links:
Host Site Page Links EcoGene.org EG13110 EcoliWiki ispD - Comment:
- isoprenoid biosynthesis: deoxyxylulose phosphate pathway for biosynthesis of terpenoids (2-C-methylerythritol-4-P plus CTP to 4-diP-cytidyl-2-C-methylerythritol-4-P).DXP path alternative to mevalonate
- References:
- Rohdich, F, J Wungsintaweekul, M Fellermeier, S Sagner, S Herz, K Kis, W Eisenreich, A Bacher, MH Zenk 1999. Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol. Proc. Natl. Acad. Sci. U.S.A. 96(21):11758-63.
- Richard, S.B., M.E. Bowman, W. Kwiatkowski, C. Chow, A.M. Lillo, D.E. Cane, J.P. Noel 2001. Structure of 4-diphosphocytidyl-2-C-methylerythritol synthetase involved in mevalonate-independent isoprenoid biosynthesis. Nat.Struct.Biol. 8:641-648