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Site galR
- Name: galR
- Type: Gene
- Synonyms
b2837 MG1655 locus tag - Mnemonic: Galactose
- Left End Point: 64.12
- Right End Point: 64.14
- Products:
repressor of galETK operon - Direction: >
- Priority: 1
- 3 Alleles of This Gene
galR34 galR61(Const) galR762(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10364 EcoliWiki galR - Comment:
- Selectable phenotype. galR^c: growth on galactose + thiomethylgalactoside. In DE ptsHI: growth on glucose; galR^n, galU- diploid for gal operon: galactose resistance.
- References:
- Buttin, G. 1963. Mecanismes regulateurs dans la biosynthese des enzymes du metabolisme du galactose chez Escherichia coli K12. II. Le determinisme genetique de la regulation. J.Mol.Biol. 7:183-205
- Saedler, H., A. Gullon, P. Starlinger 1968. Negative control of the galactose operon in E. coli. Mol.Gen.Genet. 102:79-88
- Lengeler, J.W. 1980. Characterization of mutants of Escherichia coli K12, selected by resistance to streptozotocin. Mol.Gen.Genet. 179:49-54
- MacPherson, A.J.S., M.C. Jones-Mortimer, P.J.F. Henderson 1981. Identification of the AraE transport protein of Escherichia coli. Biochem.J. 196:269-283
- von Wilcken-Bergmann, B., B. Muller-Hill 1982. Sequence of galR gene indicates a common evolutionary origin of lac and gal repressor in Escherichia coli. Proc.Natl.Acad.Sci.USA 79:2427-2431
- Weichert, M.J., S. Adhya 1992. A family of bacterial regulators homologous to Gal and Lac repressors. J.Biol.Chem. 267:15869-15874
- Weichert, M.J., S. Adhya 1993. The galactose regulon of Escherichia coli. Mol.Microbiol. 10:245-251
- Weichert, M.J., S. Adhya 1993. Control of transcription of Gal repressor and isorepressor genes in Escherichia coli. J.Bacteriol. 175:251-258
- Zhou, Y.N., S. Chatterjee, S. Roy, S. Adhya 1995. The non-inducible nature of super-repressors of the gal operon in Escherichia coli. J.Mol.Biol. 253:414-425
- Geanacopoulos, M., S. Adhya 1997. Functional characterization of roles of GalR and GalS as regulators of the gal regulon. J.Bacteriol. 179:228-234