E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site macA

• Name: macA
• Type: Gene
  Synonyms

  b0878	MG1655 locus tag
  ybjY	temporary name (EcoGene, Rudd)

  
  
• Mnemonic: Macrolide resistance
• Left End Point: 19.80
• Right End Point: 19.82
  Products:

  macrolide-specific ABC-type efflux carrier

  
  
• Direction: >
• Properties:

  Property	Comment
  encodes membrane protein	peripheral membrane protein
  ABC	NULL
  eryR	erythromycin/macrolide resistance in multicopy

  
  
• Priority: 0
  2 Alleles of This Gene

  macA779(del)::kan

  macA791-YFP(::cat)

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG13694
  EcoliWiki	macA

  
  
• Comment:
  • In multicopy, erythromycin resistance, reduced accumulation of C14-erythromycin
• References:
  • Kobayashi, N., K. Nishino, A. Yamaguchi 2001. Novel macrolide-specific ABC-type efflux transporter in Escherichia coli. J.Bacteriol. 183:5639-5644