Site fadR
- Name: fadR
- Type: Gene
- Synonyms
b1187 MG1655 locus tag dec ole thdB - Mnemonic: Fatty acid degradation
- Left End Point: 26.60
- Right End Point: 26.62
- Direction: >
- Priority: 1
- 10 Alleles of This Gene
fadR16 fadR200 fadR201 fadR202 fadR3115::Tn10kan fadR41(ts) fadR601 fadR613::Tn10 fadR776(del)::kan fadR795-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank X08087 EcoGene.org EG10281 EcoliWiki fadR - Comment:
- negative regulatory gene for fad regulon (fatty acid transport and beta-oxidation, unsaturated f.a. biosynthesis and glyox.shunt enzymes). fadR^c, including deletions: growth on decanoate.
- References:
- Simons, R.W., K.T. Hughes, W.D. Nunn, P.A. Egan, H.T. Chute 1980. Regulation of fatty acid degradation in Escherichia coli: isolation and characterization of strains bearing insertion and temperature-sensitive mutations in gene fadR. J.Bacteriol. 142:
- Simons, R.W., K.T. Hughes, W.D. Nunn 1980. Regulation of fatty acid degradation in Escherichia coli: dominance studies with strains merodiploid in gene fadR. J.Bacteriol. 143:726-730
- Clark, D.. 1981. Regulation of fatty acid degradation in Escherichia coli: analysis by operon fusion. J.Bacteriol. 148:521-526
- Maloy, S.R., W.D. Nunn 1982. Genetic regulation of the glyoxylate shunt in Escherichia coli K-12. J.Bacteriol. 149:173-180
- Wild, J.R., J. Henning, M. Lobockz, W. Walczak, T. Klopotowski 1985. Identification of the dadX gene coding for the predominant isozyme of alanine racemase in Escherichia coli K12. Mol.Gen.Genet. 198:315-322
- DiRusso, C.C., W.D. Nunn 1985. Cloning and characterization of a gene fadR involved in regulation of fatty acid metabolism in Escherichia coli. J.Bacteriol. 161:583-588
- Abdulrashid, N., D.P. Clark 1987. Isolation and genetic analysis of mutations allowing the degradation of furans and thiophenes by Escherichia coli. J.Bacteriol. 169:1267-1271
- DiRusso, C.C. 1988. Nucleotide sequence of the fadR gene, a multifunctional regulator of fatty acid metabolism in Escherichia coli. Nucleic Acids Res. 16:7995-8009
- Herold, C., E.A. Birge 1990. Location of icdA and fadR on the physical map of Escherichia coli. J.Bacteriol. 172:6618
- Farewell, A., A.A. Diez, C.C. DiRusso, T. Nystrom 1996. Role of the Escherichia coli FadR regulator in stasis survival and growth phase-dependent expression of the uspA, fad, and fab genes. J.Bacteriol. 178:6443-6450