Site dnaJ
- Name: dnaJ
- Type: Gene
- Synonyms
b0015 MG1655 locus tag groP grpC - Mnemonic: DNA
- Left End Point: 0.31
- Right End Point: 0.33
- Products:
chaperone DnaJ, regulator of DnaK-like proteins for renaturation following stress protein disulfide isomerase activity, as novel second function - Direction: >
- Properties:
Property Comment stress response heat shock heat shock regulon NULL autogenously regulated autoregulation of heat shock response - Priority: 1
- 3 Alleles of This Gene
dnaJ259(ts) dnaJ735(del)::kan dnaJ794-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank M12544 FlyBase FBgn0002174 FlyBase FBgn0015657 FlyBase FBgn0016538 FlyBase FBgn0019889 FlyBase FBgn0020129 EcoGene.org EG10240 EcoliWiki dnaJ - Comment:
- DNA biosynthesis. Selectable Phenotype. Large colonies on plates with phage LAM and phage 434 mutants. Survival of mutant phage LAM induction, survival of coinfection with mutant phage LAM & phage P2.
- References:
- Georgopoulos, C. 1971. Bacterial mutants in which the gene N function of bacteriophage lambda is blocked have an altered RNA polymerase. Proc.Natl.Acad.Sci.USA 68:2977-2981
- Paetz, W., G. Nass 1973. Biochemical and immunological characterization of threonyl-tRNA synthetase of two borrelidin-resistant mutants of Escherichia coli K-12. Eur.J.Biochem. 35:331-337
- Sunshine, M., M. Feiss, J. Stuart, J. Yochem 1977. A new host gene (groPC) necessary for lambda DNA replication. Mol.Gen.Genet. 151:27-34
- Saito, H, H Uchida 1977. Initiation of the DNA replication of bacteriophage lambda in Escherichia coli K12. 113(1):1-25.
- Yamagata, H., N. Taguchi, K. Daishima, S. Mizushima 1983. Genetic characterization of a gene for prolipoprotein signal peptidase in Escherichia coli. Mol.Gen.Genet. 192:10-14
- Bardwell, J.C., K. Tilly, E.A. Craig, J. King, M. Zylicz, C. Georgopoulos 1986. The nucleotide sequence of the Escherichia coli K12 and dnaJ+ gene: a gene that encodes a heat shock protein. J.Biol.Chem. 261:1782-1785
- Ohki, M., F. Tamura, S. Nishimura, H. Uchida 1986. Nucleotide sequence of the Escherichia coli dnaJ gene and purification of the gene product. J.Biol.Chem. 261:1778-1781
- Ohki, R., R. Morita, T. Kawamata, H. Uchida, M. Ohki 1989. A complete deletion mutant of the Escherichia coli dnaKdnaJ operon. Biochim.Biophys.Acta 1009:94-98
- Straus, D., W. Walter, C.A. Gross 1990. DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32. Genes Dev. 4:2202-2209
- Shi, W., Y. Zhou, J. Wild, J. Adler, C.A. Gross 1992. DnaK, DnaJ, and GrpE are required for flagellum synthesis in Escherichia coli. J.Bacteriol. 174:6256-6263
- Ohki, R., T. Kawamata, Y. Katoh, F. Hosoda, M. Ohki 1992. Escherichia coli dnaJ deletion mutation results in loss of stability of a positive regulator, CRP. J.Biol.Chem. 267:13180-13184
- de Crouy-Chanel, A., M. Kohiyama, G. Richarme 1995. A novel function of Escherichia coli chaperone DnaJ. Protein-disulfide isomerase. J.Biol.Chem. 270:22669-22672
- Jubete, Y., M.R. Maurizi, S. Gottesman 1996. Role of the heat shock protein DnaJ in the lon-dependent degradation of naturally unstable proteins. J.Biol.Chem. 271:30798-30803
- Pierpaoli, E.V., E. Sandmeier, H.J. Schonfeld, P. Christen 1998. Control of the DnaK chaperone cycle by substoichiometric concentrations of the co-chaperones DnaJ and GrpE. J.Biol.Chem. 273:6643-6649