Site cyaA
- Name: cyaA
- Type: Gene
- Synonyms
b3806 MG1655 locus tag - Mnemonic: cyclase, ad
- Left End Point: 85.98
- Right End Point: 86.03
- Products:
adenylate cyclase - Direction: >
- Priority: 1
- 9 Alleles of This Gene
cyaA1 cyaA1400(del)(::kan) cyaA1403(del)::kan cyaA1404(del)::FRT cyaA161 cyaA2(del) cyaA201(del) cyaA751(del)::kan cyaA854(del) - External Database Links:
Host Site Page Links EcoGene.org EG10170 EcoliWiki cyaA - Comment:
- Selec.Phen. Loss: phage lambda res. on arabinose + mal indic.plates; phage lambda + nalid. acid. res. Loss: in relA-: L-ser. resis. Dir. of transcription corrected from '90 map.
- References:
- Brickman, E., L. Soll, J.R. Beckwith 1973. Genetic characterization of mutations which affect catabolite-sensitive operons in Escherichia coli, including deletions of the gene for adenyl cyclase. J.Bacteriol. 116:582-587
- Kumar, A., V.F. Maples, W.S. Champney 1976. Properties of adenyl cyclase and cyclic adenosine 3',5'-monophosphate receptor protein-deficient mutants of Escherichia coli. J.Bacteriol. 125:545-555
- Daniel, J., A. Danchin 1979. Involvement of cyclic AMP and its receptor protein in the sensitivity of Escherichia coli K12 toward serine. Mol.Gen.Genet. 176:343-350
- Roy, A.M., A. Danchin 1981. Restriction map of the cya region of the Escherichia coli K12 chromosome. Biochimie 63:719-722
- Bankaitis, V.A., P.J. Bassford 1982. Regulation of adenylate cyclase synthesis in Escherichia coli: studies with cya-lac operon and protein fusion strains. J.Bacteriol. 151:1346-1357
- Roy, A.M., A. Danchin 1982. The cya locus of Escherichia coli K12: organization and gene products. Mol.Gen.Genet. 188:465-471
- Aiba, H., M. Kawamukai, A. Ishihama 1983. Cloning and promoter analysis of the {it Escherichia coli} adenylate cyclase gene. Nucleic Acids Res. 11:3451-3465
- Roy, A.M., C. Haziza, A. Danchin 1983. Regulation of adenylate cyclase synthesis: nucleotide sequence of the control region. EMBO J. 2:791-797
- Koop, A.H., M. Hartley, S. Bourgeois 1984. Analysis of the cya locus of Escherichia coli. Gene 28:133-146
- Aiba, H., K. Mori, M. Tanaka, T. Ooi, A.M. Roy, A. Danchin 1984. The complete nucleotide sequence of the adenylate cyclase gene of Escherichia coli. Nucleic Acids Res. 12:9427-9440
- Aiba, H. 1985. Transcription of the Escherichia coli adenylate cyclase gene is negatively regulated by cAMP-cAMP receptor protein. J.Biol.Chem. 260:3063-3070
- Thomas, S.D., P.M. Jordan 1986. Nucleotide sequence of the hemC locus encoding porphobilinogen deaminase of Escherichia coli K12. Nucleic Acids Res. 14:6215-6226
- Knott, V., D.J.G. Rees, Z. Cheng, G.G. Brownlee 1988. Randomly picked cosmid clones overlap the pyrB and oriC gap in the physical map of the E. coli chromosome. Nucleic Acids Res. 16:2601-2612
- Aldea, M., V.F. Maples, S.R. Kushner 1988. Generation of a detailed physical and genetic map of the ilv-metE-udp region of the Escherichia coli chromosome. J.Mol.Biol. 200:427-438
- Delaney, J.M. 1990. A cya deletion mutant of Escherichia coli develops thermotolerance but does not exhibit a heat-shock response. Genet.Res. 55:1-6
- Daniels, D.L., G. Plunkett, V.D. Burland, F.R. Blattner 1992. Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes. Science 257:771-778
- Puyo, M.F., P. Calsou, B. Salles 1992. UV resistance of E. coli K-12 deficient in cAMP/CRP regulation. Mutat.Res. 282:247-252
- Kimata, K., H. Takahashi, T. Inada, P. Postma, H. Aiba 1997. cAMP receptor protein-cAMP plays a crucial role in glucose-lactose diauxie by activating the major glucose transporter gene in Escherichia coli. Proc.Natl.Acad.Sci.USA 94:12914-12919
- Liu, X., T. Ferenci 2001. An analysis multifactorial influences on the transcriptional control ompF and ompC porin expression under nutrient limitation. Microbiology 147:2981-2989