Site mobA
- Name: mobA
- Type: Gene
- Synonyms
b3857 MG1655 locus tag chlB narB - Mnemonic: molybdenum
- Left End Point: 87.06
- Right End Point: 87.08
- Products:
FA protein - Direction: <
- Priority: 1
- 3 Alleles of This Gene
mobA2 mobA720(del)::kan mobA791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG11829 EcoliWiki mobA - Comment:
- biosynthesis of molybdopterin. Selectable Phenotype. Loss: chlorate resistance. Loss: growth on lactate & fumarate anaerobically. unable to attach GMP moiety to molybdopterin to form active cofactor
- References:
- Adhya, S., P.P. Cleary, A. Campbell 1968. A deletion analysis of prophage lambda and adjacent genetic regions. Proc.Natl.Acad.Sci.USA 61:956-962
- Casse, F. 1970. Mapping of the gene chlB controlling membrane bound nitrate reductase and formic hydrogen-lyase activities in Escherichia coli K-12. Biochem.Biophys.Res.Commun. 39:429-436
- Glaser, J.H., J.A. DeMoss 1972. Comparison of nitrate reductase mutants of Escherichia coli selected by alternative procedures. Mol.Gen.Genet. 116:1-10
- Lambden, P.R., J.R. Guest 1976. A novel method for isolating chlorate-resistant mutants of Escherichia coli K12 by anaerobic selection on a lactate plus fumarate medium. J.Gen.Microbiol. 93:173-176
- Fimmel, A.L., B.A. Haddock 1979. Use of chlC-lac fusions to determine regulation of gene chlC in Escherichia coli K-12. J.Bacteriol. 138:726-730
- del Campillo-Campbell, A., A. Campbell 1982. Molydbenum cofactor requirement for biotin sulfoxide reduction in Escherichia coli. J.Bacteriol. 149:469-478
- Bachmann, B.J. 1983. Linkage map of Escherichia coli K-12, edition 7. Microbiol.Rev. 47:180-230
- Preiss, J., A. Kleinhofs, W. Klingmuller 1987. Cloning of seven differently complementing DNA fragments with chl functions from Escherichia coli K12. Mol.Gen.Genet. 206:352-355
- Shanmugam, K.T., V.J. Stewart, R.P. Gunsalus, D.H. Boxer, J.A. Cole, M. Chippaux, J.A. DeMoss, G. Giordano, E.C.C. Lin, K.V. Rajagopalan 1992. Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typh
- Plunkett, G., V.D. Burland, D.L. Daniels, F.R. Blattner 1993. Analysis of the Escherichia coli genome. III. DNA sequence of the region from 87.2 to 89.2 minutes. Nucleic Acids Res. 21:3391-3398
- Palmer, T., A. Vasishta, P.W. Whitty, D.H. Boxer 1994. Isolation of protein FA, a product of the mob locus required for molybdenum cofactor biosynthesis in Escherichia coli. Eur.J.Biochem. 222:687-692
- Pogliano, J.A., J.R. Beckwith 1994. SecD and SecF facilitate protein export in Escherichia coli. EMBO J. 13:554-561
- Iobbi-Nivol, C., T. Palmer, P.W. Whitty, E. McNairn, D.H. Boxer 1995. The mob locus of Escherichia coli K12 required for molybdenum cofactor biosynthesis is expressed at very low levels. Microbiology 141:1663-1671
- Rothery, R.A., J.L. Grant, J.L. Johnson, K.V. Rajagopalan, J.H. Weiner 1995. Association of molybdopterin guanine dinucleotide with Escherichia coli dimethyl sulfoxide reductase: effect of tungstate and a mob mutation. J.Bacteriol. 177:2057-2063
- Palmer, T., C.L. Santini, C. Iobbi-Nivol, D.J. Eaves, D.H. Boxer, G. Giordano 1996. Involvement of the narJ and mob gene products in distinct steps in the biosynthesis of the molybdoenzyme nitrate reductase in Escherichia coli. Mol.Microbiol. 20:875-88
- Rothery, R.A., A. Magalon, G. Giordano, B. Guigliarelli, F. Blasco, J.H. Weiner 1998. The molybdenum cofactor of Escherichia coli nitrate reductase A (NarGHI).Effect of a mobAB mutation and interactions with [Fe-S] clusters. J.Biol.Chem. 273:7462-7469