Product B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
|B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase|
|methionine synthase, cobalamin-dependent|
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transfers methyl group from methylcobalamin enzyme to homocysteine to generate methionine and cob(I)alamin enzyme and then from MeTHF to cob(I) enz. to THF and MeCob enz.
- Amaratunga, M., K. Fluhr, J.T. Jarrett, C.L. Drennan, M.L. Ludwig, R.G. Matthews, J.D. Scholten 1996. A synthetic module for the metH gene permits facile mutagenesis of the cobalamin-binding region of Escherichia coli methionine synthase: initial chara
- Jarrett, J.T., C.Y. Choi, R.G. Matthews 1997. Changes in protonation associated with substrate binding and Cob(I)alamin formation in cobalamin-dependent methionine synthase. Biochemistry 36:15739-15748