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Product RNA polymerase, alpha subunit
| RNA polymerase, alpha subunit |
contact site for transcriptional activator proteins and for promoter UP element (Jeon et al.) and key role in assembly of core enzy. Initiator for RNAP assembly
- Jeon, Y.H., T. Negishi, M. Shirakawa, T. Yamazaki, N. Fujita, A. Ishihama, Y. Kyogoku 1995. Solution structure of the activator contact domain of the RNA polymerase alpha subunit. Science 270:1495-0
- Erijman, L., R.M. Clegg 1995. Heterogeneity of E.coli RNA polymerase revealed by high pressure. J.Mol.Biol. 253:259-0
- Polyakov, A., E. Severinova, S.A. Darst 1995. Three-dimensional structure of E.coli core RNA polymerase: promoter binding and elongation conformations of the enzyme. Cell 83:365-0
- Ozoline, O.N., M.A. Tsyganov 1995. Structure of open promoter complexes with Escherichia coli RNA polymerase as revealed by the DNase I footprinting technique: compilation analysis. Nucleic Acids Res. 23:4533-0
- Kimura, M., A. Ishihama 1995. Functional map of the alpha subunit of Escherichia coli RNA polymerase: amino acid substitution within the amino-terminal assembly domain. J.Mol.Biol. 254:342-349
- Heyduk, T., E. Heyduk, K. Severinov, H. Tang, R.H. Ebright 1996. Determinants of RNA polymerase alpha subunit for interaction with beta, beta', and sigma subunits: hydroxyl-radical protein footprinting. Proc.Natl.Acad.Sci.USA 93:10162-10166
- Lloyd, G.S., S.J. Busby, N.J. Savery 1998. Spacing requirements for interactions between the C-terminal domain of the alpha subunit of Escherichia coli RNA polymerase and the cAMP receptor protein. Biochem.J. 330:413-420
- Davenport, R.J., G.J. Wuite, R. Landick, C. Bustamante 2000. Single-molecule study of transcriptional pausing and arrest by E.coli RNA polymerase. Science 287:2497-2500
- Noel, R.J., W.S. Reznikoff 2000. Structural studies of lacUV5-RNA polymerase interactions in vitro.Ethylation interference and missing nucleoside analysis. J.Biol.Chem. 275:7708-7712
- Heyduk, E., N. Baichoo, T. Heyduk 2001. Interaction the alpha-subunit Escherichia coli RNA polymerase with DNA: rigid body nature the protein-DNA contact. J.Biol.Chem. 276:44598-44603
- Darst, S.A., N. Opalka, P. Chacon, A. Polyakov, C. Richter, G. Zhang, W. Wriggers 2002. Conformational flexibility of bacterial RNA polymerase. Proc.Natl.Acad.Sci.USA 99:4296-4301