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Product DegP protease, periplasmic endoprotease
| DegP protease, periplasmic endoprotease |
| Protease Do |
a serine protease with consensus seq.of trypsin-like proteases. Forms dodecamers, large oligomeric complex typical of intracellular proteases. See also DegQ. Degrades casein and globin.
- Seol, J.H., S.K. Woo, E.M. Jung, S.J. Yoo, C.S. Lee, K.J. Kim, K. Tanaka, A. Ichihara, D.B. Ha, C.H. Chung 1991. Protease Do is essential for survival of Escherichia coli at high temperatures: its identity with the htrA gene product. Biochem.Biophys.Re
- Skorko-Glonek, J., A. Wawrzynow, K. Krzewski, K. Kurpierz, B. Lipinska 1995. Site-directed mutagenesis of the HtrA (DegP) serine protease, whose proteolytic activity is indispensable for Escherichia coli survival at elevated temperatures. Gene 163:47-0
- Kolmar, H., P.R. Waller, R.T. Sauer 1996. The DegP and DegQ periplasmic endoproteases of Escherichia coli: specificity for cleavage sites and substrate conformation. J.Bacteriol. 178:5925-5929