Product a protein disulfide isomerase (PDI), or PDI-like protein
|a protein disulfide isomerase (PDI), or PDI-like protein|
PDI or PDI-like proteins act in the periplasm, and are located in periplasm or the inner membrane with active site facing periplasm. Oxidize diS bonds or rearrange wrongly paired diS bonds in exported proteins. By contrast, cytopl.more reducing, few diS.
- Guilhot, C., G. Jander, N.L. Martin, J.R. Beckwith 1995. Evidence that the pathway of disulfide bond formation in Escherichia coli involves interactions between the cysteines of DsbB and DsbA. Proc.Natl.Acad.Sci.USA 92:9895-9899
- Missiakas, D., J.M. Betton, S. Raina 1996. New components of protein folding in extracytoplasmic compartments of Escherichia coli SurA, FkpA and Skp/OmpH. Mol.Microbiol. 21:871-884