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Product manganese transporter, perhaps other divalent cations (Cd++), not Fe,Mg,Ca++
| manganese transporter, perhaps other divalent cations (Cd++), not Fe,Mg,Ca++ |
| NRAMP (NRM) homolog (mammalian resistance to Salmonella, etc.) |
NRAMP: natural resistance-associated macrophage proteins. Divalent transition metal transporters that may act by sequestration of Fe and Mn cofactors of catalases and SODs, to protect macrophage and deny protection to pathogen.
- Maguire, M.E. 1999. Pers.Comm. 5-:99
- Kehres, D.G., M.L. Zaharik, B.B. Finlay, M.E. Maguire 2000. The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen. Mol.Microbiol. 36:1085-1100