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Site pcnB
- Name: pcnB
- Type: Gene
- Synonyms
b0143 MG1655 locus tag - Mnemonic: plasmid copy number
- Left End Point: 3.40
- Right End Point: 3.43
- Products:
polyA polymerase I PAPI - Direction: <
- Priority: 1
- 4 Alleles of This Gene
pcnB759(del)::kan pcnB791-YFP(::cat) pcnB80 pcnB90(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank M20574 EcoGene.org EG10690 EcoliWiki pcnB - Comment:
- Plasmid copy number
- References:
- Lopilato, J., S. Bortner, J.R. Beckwith 1986. Mutations in a new chromosomal gene of Escherichia coli K-12, pcnB, reduce plasmid copy number of pBR322 and its derivatives. Mol.Gen.Genet. 205:285-290
- March, J.B., M.D. Colloms, D. Hart-Davis, I.R. Oliver, M. Masters 1989. Cloning and characterization of an Escherichia coli gene, pcnB, affecting plasmid copy number. Mol.Microbiol. 3:903-910
- Liu, J.D., J.S. Parkinson 1989. Genetics and sequence analysis of the pcnB locus, an Escherichia coli gene involved in plasmid copy number control. J.Bacteriol. 171:1254-1261
- Masters, M., J.B. March, I.R. Oliver, J.F. Collins 1990. A possible role for the pcnB gene product of Escherichia coli in modulating RNA: RNA interactions. Mol.Gen.Genet. 220:341-344
- Cao, G.J., N. Sarkar 1992. Identification of the gene for an Escherichia coli poly(A) polymerase. Proc.Natl.Acad.Sci.USA 89:10380-10384
- He, L., F. Soderbom, E.G. Wagner, U. Binnie, N. Binns, M. Masters 1993. PcnB is required for the rapid degradation of RNAI, the antisense RNA that controls the copy number of ColE1-related plasmids. Mol.Microbiol. 9:1131-1142
- Masters, M., M.D. Colloms, I.R. Oliver, L. He, E.J. MacNaughton, Y. Charters 1993. The pcnB gene of Escherichia coli, which is required for ColE1 copy number maintenance, is dispensable. J.Bacteriol. 175:4405-4413
- Raynal, L.C., H.M. Krisch, A.J. Carpousis 1996. Bacterial poly(A) polymerase: an enzyme that modulates RNA stability. Biochimie 78:390-398
- Cao, G.J., J. Pogliano, N. Sarkar 1996. Identification of the coding region for a second poly(A) polymerase in Escherichia coli. Proc.Natl.Acad.Sci.USA 93:11580-11585