Site sbcC
- Name: sbcC
- Type: Gene
- Synonyms
b0397 MG1655 locus tag - Mnemonic: suppression of recBC
- Left End Point: 8.88
- Right End Point: 8.95
- Products:
SbcCD ATP-dependent DNA ds exonuclease and ATP-independent ss endonuclease, subunit - Direction: >
- Properties:
Property Comment encodes NA-binding protein NULL member of UvrA family of nucleotide-binding proteins - Priority: 1
- 2 Alleles of This Gene
sbcC761(del)::kan sbcC792-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank X15981 NCBI/GenBank M64787 EcoGene.org EG10927 EcoliWiki sbcC - Comment:
- Suppression of recB, recC phenotype
- References:
- Lloyd, R.G., C. Buckman 1985. Identification and genetic analysis of sbcC mutations in commonly used recBC sbcB strains of Escherichia coli K-12. J.Bacteriol. 164:836-844
- Chalker, A.F., D.R. Leach, R.G. Lloyd 1988. Escherichia coli sbcC mutants permit stable propagation of DNA replicons containing a long palindrome. Gene 71:201-205
- Naom, I.S., S.J. Morton, D.R. Leach, R.G. Lloyd 1989. Molecular organization of sbcC, a gene that affects genetic recombination and the viability of DNA palindromes in Escherichia coli K-12. Nucleic Acids Res. 17:8033-8044
- Lloyd, R.G. 1991. Linkage distortion following conjugational transfer of sbcC+ to recBC sbcBC strains of Escherichia coli. J.Bacteriol. 173:5694-5698
- Leach, D.R., R.G. Lloyd, A.F. Coulson 1992. The SbcCD protein of Esherichia coli is related to two putative nucleases in the UvrA superfamily of nucleotide-binding proteins. Genetica 87:95-100
- Connelly, J.C., D.R. Leach 1996. The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination. Genes Cells 1:285-291
- Yamamoto, K., N. Takahashi, Y. Fujitani, H. Yoshikura, I. Kobayashi 1996. Orientation dependence in homologous recombination. Genetics 143:27-36