Site prlC
- Name: prlC
- Type: Gene
- Synonyms
b3498 MG1655 locus tag opdA Salmonella map - Mnemonic: PRotein Localization
- Left End Point: 78.48
- Right End Point: 78.52
- Products:
oligopeptidase A OpdA endoprotease - Direction: <
- Properties:
Property Comment encodes a protease NULL mutations suppress lamB signal sequence muts. homologous to: Salmonella opdA - Priority: 1
- 1 Alleles of This Gene
prlC754(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank M93984 EcoGene.org EG11441 EcoliWiki prlC - Comment:
- Protein export. Salmonella homolog is opdA(oligopeptidaseA).Mutations suppress the export defect of lamB signal seq. muts. Originally placed at 71'(1987, below);phys.map at 76. Signal pep pep'ase?
- References:
- Emr, S.D., S. Hanley-Way, T.J. Silhavy 1981. Suppressor mutations that restore export of a protein with a defective signal sequence. Cell 23:79-88
- Trun, N.J., T.J. Silhavy 1987. Characterization and in vivo cloning of prlC, a suppressor of signal sequence mutations in Escherichia coli K12. Genetics 116:513-521
- Trun, N.J., T.J. Silhavy 1989. PrlC, a suppressor of signal sequence mutations in Escherichia coli, can direct the insertion of the signal sequence into the membrane. J.Mol.Biol. 205:665-676
- Conlin, C.A., N.J. Trun, T.J. Silhavy, C.G. Miller 1992. Escherichia coli prlC encodes an endopeptidase and is homologous to the Salmonella typhimurium opdA gene. J.Bacteriol. 174:5881-5887
- Conlin, C.A., C.G. Miller 1993. Location of the prlC (opdA) gene on the physical map of Escherichia coli. J.Bacteriol. 175:5731-5732