Pay an invoice 
Site hlpA
- Name: hlpA
- Type: Gene
- Synonyms
b0178 MG1655 locus tag firA ompH Salmonella map orf(skp) skp Orf upstream from firA, see Dicker, Thome refs - Mnemonic: histone-like protein
- Left End Point: 4.32
- Right End Point: 4.33
- Products:
histone-like protein HLP-I (cytoplasmic?) OmpH, outer membrane protein - Direction: >
- Priority: 1
- 2 Alleles of This Gene
hlpA781(del)::kan hlpA791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10455 EcoliWiki hlpA - Comment:
- histone-like protein HLP-I (BH1); DNA-binding. But also, OmpH homolog (see Hirvas ref.) hlpA = skp = firA. Possible chaperone or folding catalyst in extracytoplasmic compartments
- References:
- Lathe, R., H. Buc, J.-P. Lecocq, E.K.F. Bautz 1980. Prokaryotic histone-like protein interacting with RNA polymerase. Proc.Natl.Acad.Sci.USA 77:3548-3552
- Aasland, R.J., J. Coleman, A.L. Holck, C.L. Smith, C.R.H. Raetz, K. Kleppe 1988. Identity of the 17-kilodalton protein, a DNA-binding protein from Escherichia coli, and the firA gene product. J.Bacteriol. 170:5916-5918
- Holck, A.L., K. Kleppe 1988. Cloning and sequencing of the gene for the DNA-binding 17K protein of Escherichia coli. Gene 67:117-124
- Coleman, J., C.R.H. Raetz 1988. First committed step of lipid A biosynthesis in Escherichia coli: sequence of the lpxA gene. J.Bacteriol. 170:1268-1274
- Hirvas, L., J. Coleman, P. Koski, M. Vaara 1990. Bacterial "histone-like protein I" (HLP-I) is an outer membrane constituent?. FEBS Lett. 262:123-126
- Thome, B.M., H.K. Hoffschulte, E. Schiltz, M. Muller 1990. A protein with sequence identity to Skp (FirA) supports protein translocation into plasma membrane vesicles of Escherichia coli. FEBS Lett. 269:113-116
- Thome, B.M., M. Muller 1991. Skp is a periplasmic Escherichia coli protein requiring SecA and SecY for export. Mol.Microbiol. 5:2815-2821
- Dicker, I.B., S. Seetharam 1991. Cloning and nucleotide sequence of the firA gene and the firA200(Ts) allele from Escherichia coli. J.Bacteriol. 173:334-344
- Hirvas, L., P. Koski, M. Vaara 1991. The ompH gene of Yersinia enterocolitica: cloning, sequencing, expression, and comparison with known enterobacterial ompH sequences. J.Bacteriol. 173:1223-1229
- Helander, I.M., B. Lindner, U. Seydel, M. Vaara 1993. Defective biosynthesis of the lipid A component of temperature-sensitive firA (omsA) mutant of Escherichia coli. Eur.J.Biochem. 212:363-369
- Chen, R., U. Henning 1996. A periplasmic protein (Skp) of Escherichia coli selectively binds a class of outer membrane proteins. Mol.Microbiol. 19:1287-1294
- Missiakas, D., J.M. Betton, S. Raina 1996. New components of protein folding in extracytoplasmic compartments of Escherichia coli SurA, FkpA and Skp/OmpH. Mol.Microbiol. 21:871-884