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Site fis
- Name: fis
- Type: Gene
- Synonyms
b3261 MG1655 locus tag nbp ndh-binding protein - Mnemonic: factor for inversion stimulation
- Left End Point: 73.48
- Right End Point: 73.49
- Products:
transcriptional activator FIS of rRNA and other genes - Direction: >
- Properties:
Property Comment encodes NA-binding protein bends DNA. plus dir.interx.with RNAP. regulatory gene 10X stimul.of rRNA operons and therefore ribosome synthesis;also tRNA, and site-spec.invers.&Lam excis. - Priority: 1
- 1 Alleles of This Gene
fis-779(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10317 EcoliWiki fis - Comment:
- Site-specific DNA inversion. nucleoid-associated.
- References:
- Koch, J.P., J. Vandekerckhove, R. Kahmann 1988. Escherichia coli host factor for site-specific DNA inversion: cloning and characterization of the fis gene. Proc.Natl.Acad.Sci.USA 85:4237-4241
- Johnson, R.C., C.A. Ball, D. Pfeffer, M.I. Simon 1988. Isolation of the gene encoding the Hin recombinational enhancer binding protein. Proc.Natl.Acad.Sci.USA 85:3484-3488
- Ross, W., J.F. Thompson, J.T. Newlands, R.L. Gourse 1990. E.coli Fis protein activates ribosomal RNA transcription in vitro. EMBO J. 9:3733-3742
- Bosch, L., L. Nilsson, E. Vijgenboom, H. Verbeek 1990. Fis-dependent trans-activation of tRNA and rRNA operons of Escherichia coli. Biochim.Biophys.Acta 1050:293-301
- Gille, H.J., J.B. Egan, A.F. Roth, W. Messer 1991. The FIS protein binds and bends the origin of chromosomal DNA replication, oriC, of Escherichia coli. Nucleic Acids Res. 19:4167-4172
- Verbeek, H., L. Nilssoj, L. Bosch 1992. The mechanism of trans-activation of the Escherichia coli operon thrU(tufB) by the protein FIS - a model. Nucleic Acids Res. 20:4077
- Filutowicz, M., W. Ross, J.R. Wild, R.L. Gourse 1992. Involvement of Fis protein in replication of the Escherichia coli chromosome. J.Bacteriol. 174:398-407
- Gosink, K.K., W. Ross, S. Leirmo, R. Osuna, S. Finkel, R.C. Johnson, R.L. Gourse 1993. DNA binding and bending are necessary but not sufficient for Fis-dependent activation of rrnB P1. J.Bacteriol. 175:1580-1589
- Augustin, L.B., B.A. Jacobson, J.A. Fuchs 1994. Escherichia coli Fis and DnaA proteins bind specifically to the nrd promoter region and affect expression of an nrd-lac fusion. J.Bacteriol. 176:378-387
- Xu, J., R.C. Johnson 1995. Fis activates the RpoS-dependent stationary-phase expression of proP in Escherichia coli. J.Bacteriol. 177:5222-5231
- Xu, J., R.C. Johnson 1995. Identification of genes negatively regulated by Fis: Fis and RpoS comodulate growth-phase-dependent gene expression in Escherichia coli. J.Bacteriol. 177:938-947
- Gonzalez-Gil, G., P. Bringmann, R. Kahmann 1996. FIS is a regulator of metabolism in Escherichia coli. Mol.Microbiol. 22:21-29
- Green, J., M.F. Anjum, J.R. Guest 1996. The ndh-binding protein (Nbp) regulates the ndh gene of Escherichia coli in response to growth phase and is identical to Fis. Mol.Microbiol. 20:1043-1055
- Zhang, X., H. Bremer 1996. Effects of Fis on ribosome synthesis and activity and on rRNA promoter activities in Escherichia coli. J.Mol.Biol. 259:27-40
- Wold, S., E. Crooke, K. Skarstad 1996. The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro. Nucleic Acids Res. 24:3527-3532
- Falconi, M., A. Brandi, A. La Teana, C.O. Gualerzi, C.L. Pon 1996. Antagonistic involvement of FIS and H-NS proteins in the transcriptional control of hns expression. Mol.Microbiol. 19:965-975
- Gosink, K.K., T. Gaal, A.J.t. Bokal, R.L. Gourse 1996. A positive control mutant of the transcription activator protein FIS. J.Bacteriol. 178:5182-5187
- Martin, R.G., J.L. Rosner 1997. Fis, an accessorial factor for transcriptional activation of the mar (multiple antibiotic resistance) promoter of Escherichia coli in the presence of the activator MarA, SoxS, or Rob. J.Bacteriol. 179:7410-7419
- Perkins-Balding, D., D. Prabha Dias, A.C. Glasgow 1997. Location, degree, and direction of DNA bending associated with the Hin recombinational enhancer sequence and Fis-enhancer complex. J.Bacteriol. 179:4747-4753
- Schneider, R., A. Travers, G. Muskhelishvili 1997. FIS modulates growth phase-dependent topological transitions of DNA in Escherichia coli. Mol.Microbiol. 26:519-530
- Appleman, J.A., W. Ross, J. Salomon, R.L. Gourse 1998. Activation of Escherichia coli rRNA transcription by FIS during a growth cycle. J.Bacteriol. 180:1525-1532
- Bartlett, M.S., T. Gaal, W. Ross, R.L. Gourse 2000. Regulation of rRNA transcription is remarkably robust: FIS compensates for altered nucleoside triphosphate sensing by mutant RNA polymerases at Escherichia coli rrn P1 promoters. J.Bacteriol. 182:1969
- Schneider, R., R. Lurz, G. Luder, C. Tolksdorf, A. Travers, G. Muskhelishvili 2001. An architectural role of the Escherichia coli chromatin protein FIS in organising DNA. Nucleic Acids Res. 29:5107-5114
- Nasser, W., M. Rochman, G. Muskhelishvili 2002. Transcriptional regulation of fis operon involves a module of multiple coupled promoters. EMBO J. 21:715-724
- Shin, D., N. Cho, S. Heu, S. Ryu 2003. Selective regulation of ptsG expression by Fis.Formation of either activating or repressing nucleoprotein complex in response to glucose. J.Biol.Chem. 278:14776-14781
- Walker, K.A., P. Mallik, T.S. Pratt, R. Osuna 2004. The Escherichia coli Fis promoter is regulated by changes in the levels of its transcription initiation nucleotide CTP. J.Biol.Chem. 279:50818-50828