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Site rpoD
- Name: rpoD
- Type: Gene
- Synonyms
alt b3067 MG1655 locus tag - Mnemonic: RNA polymerase
- Left End Point: 69.21
- Right End Point: 69.25
- Products:
RNA polymerase, sigma subunit sigma-70 - Direction: >
- Priority: 1
- 4 Alleles of This Gene
rpoD285(ts) rpoD758(del)::kan rpoD800(ts) rpoD899(ts) - External Database Links:
Host Site Page Links EcoGene.org EG10896 EcoliWiki rpoD - Comment:
- Selectable phenotype. Resistant to lysis by LAC cI71. In cya- or crp-: growth on L-arabinose. 70K subunit. transcribes most genes expressed in expon.cells.
- References:
- Silverstone, A.E., M. Goman, J. G. Scaife 1972. ALT: a new factor involved in the synthesis of RNA by Escherichia coli. Mol.Gen.Genet. 118:223-234
- Gross, C.A., F.R. Blattner, W.E. Taylor, P.A. Lowe, R.R. Burgess 1979. Isolation and characterization of transducing phage coding for a subunit of Escherichia coli RNA polymerase. Proc.Natl.Acad.Sci.USA 76:5789-5793
- Burgess, R.R., C.A. Gross, W. Walter, P.A. Lowe 1979. Altered chemical properties in three mutants of E. coli RNA polymerase sigma subunit. Mol.Gen.Genet. 175:251-257
- Nakamura, Y., T. Kurihara, H. Saito, H. Uchida 1979. Sigma subunit of Escherichia coli RNA polymerase affects the function of lambda N gene. Proc.Natl.Acad.Sci.USA 76:4593-4597
- Liebke, H., C.A. Gross, W. Walter, R.R. Burgess 1980. A new mutation rpoD800, affecting the sigma subunit of E. coli RNA polymerase is allelic to two other sigma mutants. Mol.Gen.Genet. 177:277-282
- Nakamura, Y. 1980. Hybrid plasmid carrying Escherichia-coli genes for primase (dnaG) and RNA polymerase sigma factor (rpoD); gene organization and control of their expression. Mol.Gen.Genet. 178:487-497
- Burton, Z.F., R.R. Burgess, J. Lin, D. Moore, S. Holder, C.A. Gross 1981. The nucleotide sequence of the cloned rpoD gene for the RNA polymerase sigma subunit from E. coli K12. Nucleic Acids Res. 9:2889-2903
- Lupski, J.R., B.L. Smiley, G.N. Godson 1983. Regulation of the rpsU-dnaG-rpoD macromolecular synthesis operon and the initiation of DNA replication in Escherichia coli K-12. Mol.Gen.Genet. 189:48-57
- Burton, Z.F., C.A. Gross, K. Watanabe, R.R. Burgess 1983. The operon that encodes the sigma subunit of RNA polymerase also encodes ribosomal protein S21 and DNA primase in E. coli K12. Cell 32:335-349
- Taylor, W.E., D.B. Straus, A.D. Grossman, Z.F. Burton, C.A. Gross, R.R. Burgess 1984. Transcription from a heat-inducible promoter causes heat shock regulation of the sigma subunit of E. coli RNA polymerase. Cell 38:371-381
- Lupski, J.R., A.A. Ruiz, G.N. Godson 1984. Promotion, termination and anti-termination of the rpsU-dnaG-rpoD macromolecular synthesis operon of E. coli K-12. Mol.Gen.Genet. 195:391-401
- Gardella, T., H. Moyle, M.M. Susskind 1989. A mutant Escherichia coli sigma 70 subunit of RNA polymerase with altered promoter specificity. J.Mol.Biol. 206:579-590
- Kumar, A., R.A. Malloch, N. Fujita, D.A. Smillie, A. Ishihama, R.S. Hayward 1993. The minus 35-recognition region of Escherichia coli sigma 70 is inessential for initiation of transcription at an "extended minus 10" promoter. J.Mol.Biol. 232:406-0
- Hernandez, V.J., M. Cashel 1995. Changes in conserved region 3 of Escherichia coli sigma 70 mediate ppGpp-dependent functions in vivo. J.Mol.Biol. 252:536-0
- Kim, S.K., K. Makino, M. Amemura, A. Nakata, H. Shinagawa 1995. Mutational analysis of the role of the first helix of region 4.2 of the sigma 70 subunit of Escherichia coli RNA polymerase in transcriptional activation by activator protein PhoB. Mol.Gen
- Davenport, R.J., G.J. Wuite, R. Landick, C. Bustamante 2000. Single-molecule study of transcriptional pausing and arrest by E.coli RNA polymerase. Science 287:2497-2500