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Site rep
- Name: rep
- Type: Gene
- Synonyms
b3778 MG1655 locus tag dasC mbrA mmrA - Mnemonic: replicase
- Left End Point: 85.32
- Right End Point: 85.37
- Products:
Rep helicase, a single-stranded DNA-dependent ATPase - Direction: >
- Properties:
Property Comment encodes helicase NULL encodes DNA-dependent ATPase NULL - Priority: 1
- 6 Alleles of This Gene
rep-142(ts) rep-3 rep-5 rep-71([]) rep-729(del)::kan rep-791-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank M11055 EcoGene.org EG10837 EcoliWiki rep - Comment:
- 11/86 N. Ossanna, D. Mount lab says that a DE{\it rep} allele was published by the Deuhardt lab in strain HB2021 1984 Gene 28:93-102. Sel. phenotype. Phage P2 resistance.
- References:
- Calendar, R., B. Lindquist, G. Sironi, A.J. Clark 1970. Characterization of REP^- mutants and their interaction with P2 phage. Virology 40:72-83
- Tessman, I., J.S. Fassler, D.C. Bennett 1982. Relative map location of the rep and rho genes of Escherichia coli. J.Bacteriol. 151:1637-1640
- Baylor, N.W., A.L. Williams, N. Cofie 1983. Molecular characteristics of ilvC specialized transducing phages of Escherichia coli K-12. Mol.Gen.Genet. 191:347-352
- Bialkowska-Hobrzanska, H., D. Denhardt 1984. The rep mutation. VII. Cloning and analysis of the functional rep gene of Escherichia coli K-12. Gene 28:93-102
- Driver, R.P., R.P. Lawther 1985. Physical analysis of deletion mutations in the ilvGEDA operon of Escherichia coli K-12. J.Bacteriol. 162:598-606
- Bialkowska-Hobrzanska, H., C.A. Gilchrist, D.T. Denhardt 1985. Escherichia coli rep gene: identification of the promoter and N terminus of the rep protein. J.Bacteriol. 164:1004-1010
- Gilchrist, C.A., D. Denhardt 1987. Escherichia coli rep gene: sequence of the gene, the encoded helicase, and its homology with uvrD. Nucleic Acids Res. 15:465-475
- Aldea, M., V.F. Maples, S.R. Kushner 1988. Generation of a detailed physical and genetic map of the ilv-metE-udp region of the Escherichia coli chromosome. J.Mol.Biol. 200:427-438
- Daniels, D.L., G. Plunkett, V.D. Burland, F.R. Blattner 1992. Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes. Science 257:771-778
- Lohman, T.M., K.P. Bjornson 1996. Mechanisms of helicase-catalyzed DNA unwinding. Annu.Rev.Biochem. 65:169-214
- Maisnier-Patin, S., K. Nordstrom, S. Dasgupta 2001. Replication arrests during a single round of replication of the Escherichia coli chromosome in the absence of DnaC activity. Molecular Microbiology 42:1371-1382