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Site frr
- Name: frr
- Type: Gene
- Synonyms
b0172 MG1655 locus tag rrf - Mnemonic: factor for ribosome recycling/release
- Left End Point: 4.16
- Right End Point: 4.17
- Products:
ribosome recycling factor ribosome releasing factor RF4 RF-4 - Direction: >
- Properties:
Property Comment essential gene NULL - Priority: 0
- 1 Alleles of This Gene
frr-791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10335 EcoliWiki frr - Comment:
- dissociates ribosomes from mRNA after temination of translation
- References:
- Ichikawa, S., A. Kaji 1989. Molecular cloning and expression of ribosome releasing factor. J.Biol.Chem. 264:20054-20059
- Ichikawa, S., M. Ryoji, Z. Siegfried, A. Kaji 1989. Localization of the ribosome-releasing factor gene in the Escherichia coli chromosome. J.Bacteriol. 171:3689-3695
- Shimizu, I., A. Kaji 1991. Identification of the promoter region of the ribosome-releasing factor cistron (ffr). J.Bacteriol. 173:5181-5187
- Janosi, L., I. Shimizu, A. Kaji 1994. Ribosome recycling factor (ribosome releasing factor) is essential for bacterial growth. Proc.Natl.Acad.Sci.USA 91:4249-4253
- Pavlov, M.Y., D.V. Freistroffer, J. MacDougall, R.H. Buckingham, M. Ehrenberg 1997. Fast recycling of Escherichia coli ribosomes requires both ribosome recycling factor (RRF) and release factor RF3 [published erratum appears in EMBO J 1997 Sep 1;16(17)
- Heurgue-Hamard, V., R. Karimi, L. Mora, J. MacDougall, C. Leboeuf, G. Grentzmann, M. Ehrenberg, R.H. Buckingham 1998. Ribosome release factor RF4 and termination factor RF3 are involved in dissociation of peptidyl-tRNA from the ribosome. EMBO J. 17:808