Site rng
- Name: rng
- Type: Gene
- Synonyms
adhR original 1985,87 papers on regul.adhE b3247 MG1655 locus tag cafA original description of cytoplasmic axial filaments - Mnemonic: RNase G
- Left End Point: 73.16
- Right End Point: 73.19
- Products:
RNase G ribonuclease G - Direction: <
- Properties:
Property Comment affects cell division/growth overprod. of CafA results in chained cells and minicells, with long axial struc ture running thru chain - Priority: 0
- 2 Alleles of This Gene
rng-1 rng-771(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11299 EcoliWiki rng - Comment:
- 34% similarity with N terminus of Ams protein which crossreacts with nonmuscle myosin heavy chain antibody. See CafA morphology above and also regul. of adhE activity.
- References:
- Miczak, A., J. Ford, M. Marian, D. Apirion 1983. RNA processing: new mutants that affect endonucleolytic processing of RNA. Biochem.Biophys.Res.Commun. 114:690-698
- Chesney, R.H., P. Sollitti, D.R. Vickery 1985. Identification of a new locus in the Escherichia coli cotransduction gap that represents a new genetic component of the L-asparagine utilization system. J.Gen.Microbiol. 131:2079-2085
- Clark, D.P., M.L. Rod 1987. Regulatory mutations that allow the growth of Escherichia coli on butanol as carbon source. J.Mol.Evol. 25:151-158
- Okada, Y., M. Wachi, A. Hirata, K. Suzuki, K. Nagai, M. Matsuhashi 1994. Cytoplasmic axial filaments in Escherichia coli cells: possible function in the mechanism of chromosome segregation and cell division. J.Bacteriol. 176:917-922
- Li, Z., S. Pandit, M.P. Deutscher 1999. RNase G (CafA protein) and RNase E are both required for the 5' maturation of 16S ribosomal RNA. EMBO J. 18:2878-2885
- Wachi, M., G. Umitsuki, M. Shimizu, A. Takada, K. Nagai 1999. Escherichia coli cafA gene encodes a novel RNase, designated as RNase G, involved in processing of the 5' end of 16S rRNA. Biochem.Biophys.Res.Commun. 259:483-488
- Wachi, M., N. Kaga, G. Umitsuki, D.P. Clark, K. Nagai 2001. A novel RNase G mutant that is defective in degradation of adhE mRNA but proficient in the processing of 16S rRNA precursor. Biochem.Biophys.Res.Commun. 289:1301-1306
- Umitsuki, G., M. Wachi, A. Takada, T. Hikichi, K. Nagai 2001. Involvement of RNase G in in vivo mRNA metabolism in Escherichia coli. Genes to Cells 6:403-410
- Kaga, N., G. Umitsuki, D.P. Clark, K. Nagai, M. Wachi 2002. Extensive overproduction of the AdhE protein by rng mutations depends on mutations in the cra gene or in the Cra-box of the adhE promoter. Biochem.Biophys.Res.Commun. 295:92-97