Pay an invoice 
Site lolB
- Name: lolB
- Type: Gene
- Synonyms
b1209 MG1655 locus tag hemM Matsuyama et al. - Mnemonic: localization OM lipoproteins
- Left End Point: 27.21
- Right End Point: 27.22
- Products:
glutamyl-tRNA dehydrogenase?? probably not outer membrane lipoprotein, LolB Lpp-LolA receptor in OMP - Direction: <
- Priority: 0
- External Database Links:
Host Site Page Links EcoGene.org EG11293 EcoliWiki lolB - Comment:
- renamed lolB? Conflicting evidence on whether it encodes GTR deHase (1992) or protein unrelated to known ALA pathway enzymes (1997). An OMP involved with LolA(p2) localization of lipoproteins into OM.
- References:
- Jahn, D., U. Michelsen, D. Soll 1991. Two glutamyl-tRNA reductase activities in Escherichia coli. J.Biol.Chem. 266:2542-2548
- Ikemi, M., K. Murakami, M. Hashimoto, Y. Murooka 1992. Cloning and characterization of genes involved in the biosynthesis of delta-aminolevulinic acid in Escherichia coli. Gene 121:127-132
- Post, D.A., B. Hove-Jensen, R.L. Switzer 1993. Characterization of the hemA-prs region of the Escherichia coli and Salmonella typhimurium chromosomes: identification of two open reading frames and implications for prs expression. J.Gen.Microbiol. 139:2
- Chen, W., C.S. Russell, Y. Murooka, S.D. Cosloy 1994. 5-aminolevulinic acid synthesis in Escherichia coli requires expression of hemA. J.Bacteriol. 176:2743-2746
- Matsuyama, S., T. Tajima, H. Tokuda 1995. A novel periplasmic carrier protein involved in the sorting and transport of Escherichia coli lipoproteins destined for the outer membrane. EMBO J. 14:3365-3372
- Matsuyama, S., N. Yokota, H. Tokuda 1997. A novel outer membrane lipoprotein, LolB (HemM), involved in the LolA (p20)-dependent localization of lipoproteins to the outer membrane of Escherichia coli. EMBO J. 16:6947-6955
- Verderber, E., L.J. Lucast, J.A. Van Dehy, P. Cozart, J.B. Etter, E.A. Best 1997. Role of the hemA gene product and delta-aminolevulinic acid in regulation of Escherichia coli heme synthesis. J.Bacteriol. 179:4583-4590
- Yokota, N., T. Kuroda, S. Matsuyama, H. Tokuda 1999. Characterization of the LolA-LolB system as the general lipoprotein localization mechanism of Escherichia coli. J.Biol.Chem. 274:30995-30999
- Wada, R., S. Matsuyama, H. Tokuda 2004. Targeted mutagenesis of five conserved tryptophan residues of LolB involved in membrane localization of Escherichia coli lipoproteins. Biochem.Biophys.Res.Commun. 323:1069-1074