Site acpS
- Name: acpS
- Type: Gene
- Synonyms
b2563 MG1655 locus tag dpj downstream of pdxJ, temporary name 1992 - Mnemonic: acyl-carrier-protein
- Left End Point: 58.17
- Right End Point: 58.18
- Products:
holo-[acyl carrier protein] synthase CoA:apo-ACP-pantetheinephosphotransferase - Direction: <
- Properties:
Property Comment essential gene NULL member of P-pantetheinyl transferase superfamily (modif. acys carrier domain via CoA) - Priority: 0
- 1 Alleles of This Gene
acpS791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10247 EcoliWiki acpS - Comment:
- acpS originally localized near 44, but that is apparently a regulatory or other acp gene that Cronan now refers to as acpX Polacco and Cronan, 1981.
- References:
- Polacco, M., J.E. Cronan 1981. A mutant of Escherichia coli conditionally defective in the synthesis of holo-[acyl carrier protein]. J.Biol.Chem. 256:5750-5754
- Lam, H.L., E. Tancula, W.B. Dempsey, M.E. Winkler 1992. Suppression of insertions in the complex pdxJ operon of Escherichia coli K-12 by lon and other mutations. J.Bacteriol. 174:1554-1567
- Takiff, H.E., T. Baker, T. Copeland, S.M. Chen, D.L. Court 1992. Locating essential Escherichia coli genes by using mini-Tn10 transposons: the pdxJ operon. J.Bacteriol. 174:1544-1553
- Lambalot, R.H., C.T. Walsh 1995. Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase. J.Biol.Chem. 270:24658-24661
- Lambalot, R.H., A.M. Gehring, R.S. Flugel, P. Zuber, M. LaCelle, M.A. Marahiel, R. Reid, C. Khosla, C.T. Walsh 1996. A new enzyme superfamily - the phosphopantetheinyl transferases. Chem. Biol. 3:923-936