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Site chpA
- Name: chpA
- Type: Gene
- Synonyms
b2782 MG1655 locus tag chpAK mazF GenBank entry ECORELA, J04039 - Mnemonic: Chromosomal Homolog of pem
- Left End Point: 62.70
- Right End Point: 62.71
- Products:
A subunit of ChpAB growth inhibitor (programmed cell death module?), toxic - Direction: <
- Properties:
Property Comment affects cell division/growth inhibits growth - Priority: 0
- 1 Alleles of This Gene
chpA781(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11249 EcoliWiki chpA - Comment:
- homolog of plasmid R100's pemK gene, a growth inhibitor. encodes a growth inhibitor. see also chpB. together, an "addiction module"/programmed cell death? mediates thymineless death.
- References:
- Masuda, Y., K. Miyakawa, Y. Nishimura, E. Ohtsubo 1993. chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100. J.Bacteriol. 175:6850-6856
- Aizenman, E., H. Engelberg-Kulka, G. Glaser 1996. An Escherichia coli chromosomal "addiction module" regulated by 3',5'-bispyrophosphate: a model for programmed bacterial cell death. Proc.Natl.Acad.Sci.USA 93:6059-6063
- Sat, B., M. Reches, H. Engelberg-Kulka 2003. The Escherichia coli mazEF suicide module mediates thymineless death. J.Bacteriol. 185:1803-1807