Site secG
- Name: secG
- Type: Gene
- Synonyms
b3175 MG1655 locus tag prlH protein localization, alleles affecting - Mnemonic: secretory (monitor)
- Left End Point: 71.56
- Right End Point: 71.57
- Products:
component of preprotein translocase p12 cytoplasmic membrane protein, auxiliary component of protein export apparatus SecE-G-Y cytoplasmic membrane translocation complex - Direction: <
- Properties:
Property Comment encodes membrane protein NULL transport gene NULL - Priority: 0
- 1 Alleles of This Gene
secG783(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG12095 EcoliWiki secG - Comment:
- contributes to signal sequence recognition and may also contribute to topology of integral membrane proteins. Auxiliary to protein export apparatus
- References:
- Nishiyama, K., S. Mizushima, H. Tokuda 1993. A novel membrane protein involved in protein translocation across the cytoplasmic membrane of Escherichia coli. EMBO J. 12:3409-3415
- Nishiyama, K., M. Hanada, H. Tokuda 1994. Disruption of the gene encoding p12 (SecG) reveals the direct involvement and important function of SecG in the protein translocation of Escherichia coli at low temperature. EMBO J. 13:3272-3277
- Douville, K., A. Price, J. Eichler, A. Economou, W. Wickner 1995. SecYEG and SecA are the stoichiometric components of preprotein translocase. J.Biol.Chem. 270:20106-20111
- Bost, S., D. Belin 1995. A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery. EMBO J. 14:4412-4421
- Wickner, W., M.R. Leonard 1996. Escherichia coli preprotein translocase. J.Biol.Chem. 271:29514-29516
- Hanada, M., K. Nishiyama, H. Tokuda 1996. SecG plays a critical role in protein translocation in the absence of the proton motive force as well as at low temperature. FEBS Lett. 381:25-28
- Bost, S., D. Belin 1997. prl mutations in the Escherichia coli secG gene. J.Biol.Chem. 272:4087-4093
- Flower, A.M., L.L. Hines, P.L. Pfennig 2000. SecG is an auxiliary component of the protein export apparatus of Escherichia coli. Mol.Gen.Genet. 263:131-136