Site pssA
- Name: pssA
- Type: Gene
- Synonyms
b2585 MG1655 locus tag - Mnemonic: phosphatidylserine synthetase
- Left End Point: 58.65
- Right End Point: 58.68
- Products:
phosphatidylserine synthase - Direction: >
- Priority: 1
- 3 Alleles of This Gene
pssA1 pssA21(ts) pssA791-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank M58699 EcoGene.org EG10781 EcoliWiki pssA - Comment:
- Selectable phenotype. Ethanol, dimethylsulfoxide resistance. Mutants make cell membranes deficient in phosphatidylethanolamine and lack motility and chemotaxis. PSS interacts with lipid bilayers
- References:
- Ohta, A, I Shibuya 1977. Membrane phospholipid synthesis and phenotypic correlation of an Escherichia coli pss mutant. J. Bacteriol. 132(2):434-43.
- Clark, D.P., J.P. Beard 1979. Altered phospholipid composition in mutants of Escherichia coli sensitive or resistant to organic solvents. J.Gen.Microbiol. 113:267-274
- Ohta, T., K. Waggoner, K. Louie, W. Dowhan 1981. Cloning of genes involved in membrane lipid synthesis. Effects of amplification of phosphatidylserine synthetase in Escherichia coli. J.Biol.Chem. 256:2219-2225
- DeChavigny, A., P.N. Heacock, W. Dowhan 1991. Sequence and inactivation of the pss gene of Escherichia coli. Phosphatidylethanolamine may not be essential for cell viability. J.Biol.Chem. 266:5323-5332
- Shi, W., M. Bogdanov, W. Dowhan, D.R. Zusman 1993. The pss and psd genes are required for motility and chemotaxis in Escherichia coli. J.Bacteriol. 175:7711-7714
- Matsumoto, K. 1997. Phosphatidylserine synthase from bacteria. Biochim.Biophys.Acta 1348:214-227